2013-06-19T09:49:00Z http://repub.eur.nl/oai

oai:repub.eur.nl/res/pub/24174 2012-11-14T12:29:34Z org:9786 org:9831 org:9830 org:9755 org:9804 org:9746 access:open type:article

urn:NBN:nl:ui:15-1765/24174 2012-11-14T12:29:34 mods http://hdl.handle.net/1765/24174 hdl:1765/24174 urn:NBN:nl:ui:15-1765/24174 doi:10.1007/s00384-009-0692-4 After-hours colorectal surgery: A risk factor for anastomotic leakage text article http://hdl.handle.net/1765/24174 http://repub.eur.nl/res/pub/24174/19301016.pdf application/pdf Filesize: 131 KB born digital Purpose: This study aims to increase knowledge of colorectal anastomotic leakage by performing an incidence study and risk factor analysis with new potential risk factors in a Dutch tertiary referral center. Methods: All patients whom received a primary colorectal anastomosis between 1997 and 2007 were selected by means of operation codes. Patient records were studied for population description and risk factor analysis. Results: In total 739 patients were included. Anastomotic leakage (AL) occurred in 64 (8.7%) patients of whom nine (14.1%) died. Median interval between operation and diagnosis was 8 days. The risk for AL was higher as the anastomoses were constructed more distally (p = 0.019). Univariate analysis showed duration of surgery (p = 0.038), BMI (p = 0.001), time of surgery (p = 0.029), prophylactic drainage (p = 0.006) and time under anesthesia (p = 0.012) to be associated to AL. Multivariate analysis showed BMI greater than 30 kg/m2(p = 0.006; OR 2.6 CI 1.3-5.2) and "after hours" construction of an anastomosis (p = 0.030; OR 2.2 CI 1.1-4.5) to be independent risk factors. Conclusion: BMI greater than 30 kg/m2and "after hours" construction of an anastomosis were independent risk factors for colorectal anastomotic leakage. Komen, N.A.P. Komen Niels aut Dijk, J.W. Dijk Jan-Willem aut Lalmahomed, Z.S. Lalmahomed Zarina aut Klop, K. Klop Karel aut Hop, W. Hop Wim aut Kleinrensink, G.J. Kleinrensink Gert Jan aut Jeekel, J. Jeekel Hans aut Ruud Schouten, W. Ruud Schouten W. aut Lange, J.F. Lange Johan aut 154262099 069209391 298685469 Erasmus MC: University Medical Center Rotterdam Supporting host sht en English International Journal of Colorectal Disease: clinical and molecular gastroenterology and surgery 0179-1958 24 7 789 795 2009-04-08 Colorectal surgery After-hours Anastomotic leakage Body mass index Erasmus University Rotterdam oai:repub.eur.nl/res/pub/24174 IR OAIPMH feed (http://repub.eur.nl/oai) 2011-08-03T14:45:18Z 2011-11-23T09:59:13Z http://purl.org/eprint/accessRights/OpenAccess