2013-05-23T08:55:52Z http://repub.eur.nl/oai

oai:repub.eur.nl/res/pub/8625 2012-11-14T12:27:59Z org:9830 org:9755 org:9821 org:9746 access:open type:article

urn:NBN:nl:ui:15-1765/8625 2012-11-14T12:27:59 mods http://hdl.handle.net/1765/8625 hdl:1765/8625 urn:NBN:nl:ui:15-1765/8625 Enzymatic method for inactivation of aminoglycosides during measurement of postantibiotic effect text article http://hdl.handle.net/1765/8625 http://repub.eur.nl/res/pub/8625/8834906.pdf application/pdf Filesize: 161 KB born digital To determine the postantibiotic effect of aminoglycosides, two methods are currently being used to remove the test drug: repeated washing and dilution. An enzymatic inactivation method of removing gentamicin and tobramycin was developed and compared with the dilution method. This enzymatic method provides a rapid and simple alternative method of removing aminoglycosides which results in reliable postantibiotic-effect values. Hollander, J.G. den Hollander, den Jan aut Mouton, J.W. Mouton Johan aut Bakker-Woudenberg, I.A.J.M. Bakker-Woudenberg Irma aut Vleggaar, F.P. Vleggaar Frank aut Goor, M.P.J. van Goor, van M.P.J. aut Verbrugh, H.A. Verbrugh Henri aut 074528688 068402856 Erasmus MC: University Medical Center Rotterdam Supporting host sht en English Antimicrobial Agents and Chemotherapy 0066-4804 1996-01-01 Comparative Study Acetyltransferases/*pharmacology Bacteria/drug effects/*metabolism Gentamicins/metabolism Microbial Sensitivity Tests/*methods Tobramycin/metabolism Anti-Bacterial Agents/*metabolism Erasmus University Rotterdam oai:repub.eur.nl/res/pub/8625 IR OAIPMH feed (http://repub.eur.nl/oai) 2007-02-13T09:22:12Z 2011-11-23T09:59:13Z http://purl.org/eprint/accessRights/OpenAccess