Effects of semantic treatment on verbal communication and linguistic processing in aphasia after stroke: a randomized controlled trial.
BACKGROUND AND PURPOSE: Semantic deficits, deficits in word meaning, have a large impact on aphasic patients' verbal communication. We investigated the effects of semantic treatment on verbal communication in a randomized controlled trial. METHODS: Fifty-eight patients with a combined semantic and phonological deficit were randomized to receive either semantic treatment or the control treatment focused on word sound (phonology). Fifty-five patients completed pretreatment and posttreatment assessment of verbal communication (Amsterdam Nijmegen Everyday Language Test [ANELT]). In an on-treatment analysis (n=46), treatment-specific effects on semantic and phonological measures were explored. RESULTS: Both groups improved on the ANELT, with no difference between groups in overall score (difference, -1.1; 95% confidence interval [CI], -5.3 to 3.1). After semantic treatment, patients improved on a semantic measure (mean improvement, 2.9; 95% CI, 1.2 to 4.6), whereas after phonological treatment, patients improved on phonological measures (mean improvement, 3.0; 95% CI, 1.4 to 4.7, and 3.0; 95% CI, 1.2 to 4.7). CONCLUSIONS: No differences in primary outcome were noted between the 2 treatments. Our findings challenge the current notion that semantic treatment is more effective than phonological treatment for patients with a combined semantic and phonological deficit. The selective gains on the semantic and phonological measures suggest that improved verbal communication was achieved in a different way for each treatment group.
|Keywords||*Verbal Behavior, Adult, Aged, Aged, 80 and over, Aphasia/etiology/*therapy, Articulation Disorders/etiology/*therapy, Cerebrovascular Accident/complications/physiopathology/*rehabilitation, Comparative Study, Female, Humans, Language Therapy/*methods, Male, Middle Aged, Neuropsychological Tests, Referral and Consultation, Research Support, Non-U.S. Gov't, Semantics, Single-Blind Method, Treatment Outcome|
|Persistent URL||dx.doi.org/10.1161/01.STR.0000105460.52928.A6, hdl.handle.net/1765/13272|
Doesborgh, S.J.C., van de Sandt-Koenderman, W.M.E., Dippel, D.W.J., van Harskamp, F., Koudstaal, P.J., & Visch-Brink, E.G.. (2004). Effects of semantic treatment on verbal communication and linguistic processing in aphasia after stroke: a randomized controlled trial.. Stroke, 35(1), 141–146. doi:10.1161/01.STR.0000105460.52928.A6