Craniofacial Distraction Osteogenesis: Effects of rhythm of distraction on bone regeneration
Distraction osteogenesis is defined as the formation of new bone tissue between bone segments that are divided by an osteotomy and then gradually separated by exerting an external force to the mobile bone segment(s). The resulting callus tissue in the distraction gap will eventually mineralize, creating a new bridge of bone between the osteotomy edges of the original bone segments. Nowadays, distraction osteogenesis is a widely accepted tool for the treatment of acquired and congenital deformities of the skull bones. Optimizing the distraction protocol would shorten the total treatment time for the patient. Our animal experimental research aimed to study the effects of rhythm of distraction in order to optimize the outcome. Our main conclusion is that a continuous rhythm of distraction shows accelerated bone formation compared with discontinuous rhythms of distraction.
|Keywords||animal model, bone, craniofacial: oral and maxillofacial, distraction osteogenesis, rabbit, regeneration, rhythm, surgery, tissue|
|Promotor||S.E.R. Hovius (Steven) , K.G.H. van der Wal (Karel)|
|Publisher||Erasmus University Rotterdam|
|Sponsor||Astra Tech Benelux BV Erasmus Universiteit Rotterdam, Harlan Netherlands BV, Martin Nederland / Marned BV, Stichting Anna Fonds, Stichting BOOA, Synthes BV, UNO Roestvaststaal BV|
Djasim, U.M.. (2008, December 3). Craniofacial Distraction Osteogenesis: Effects of rhythm of distraction on bone regeneration. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/14041