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Series-elastic properties of strips of smooth muscle from pig urinary bladder

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Abstract

The series elasticity of strips of smooth muscle from pig urinary bladder was investigated by means of a series of computerised quick-release and quick-stretch measurements with and without stimulation of the muscle, and at different shortenings and force levels. The results cannot be interpreted in terms of a discrete passive series-elastic element. They can, however, be interpreted in terms of the sliding-filaments model for contracting muscle.

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Abbreviations

a :

constant factor representing geometry of muscle

A :

coefficient of exponential crossbridge elasticity

β:

exponent of exponential crossbridge elasticity

β/lo :

exponent in elastic characteristic of discrete elastic element

ΔF s − :

corrected force decrease during stimulation and quick release (in the rising phase of the contraction)

ΔF s + :

corrected force increase during stimulation and quick stretch (in the rising phase of the contraction)

ΔF o − :

corrected force decrease after stimulation and during quick release (in the falling phase of the contraction)

ΔF o + :

corrected force increase after stimulation and during quick stretch (in the falling phase of the contraction)

Δl :

extent of quick release or stretch

Δx :

elongation of series elastic element

Eo/lo:

coefficient in elastic characteristic of discrete elastic element

F :

force

F Δl :

force measured during a quick release or quick stretch

F iso :

maximum active isometric force during contraction

F trig :

preset force-trigger level

g(X) :

force as a function of length of a crossbridge

h :

upper limit of crossbridge lengths

l :

length of muscle strip

no(t):

number of active crossbridges during an isometric contraction

n(X) :

spectrum of lengths of crossbridges

V t :

tissue volume of strip

X :

length of crossbridge

x :

macroscopic equivalent ofX obtained by additions of lengths of crossbridges which are in series

σ Δi :

force measured during a quick release or quick stretch, normalised by dividing by the cross-sectional area of the strip

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Authors and Affiliations

  1. Department of Urology, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands

    R. van Mastrigt & E. A. Tauecchio

  2. Department of Biological & Medical Physics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands

    R. van Mastrigt & E. A. Tauecchio

Authors
  1. R. van Mastrigt
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  2. E. A. Tauecchio
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van Mastrigt, R., Tauecchio, E.A. Series-elastic properties of strips of smooth muscle from pig urinary bladder. Med. Biol. Eng. Comput. 20, 585–594 (1982). https://doi.org/10.1007/BF02443406

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  • DOI: https://doi.org/10.1007/BF02443406

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