A multiplex ligation-dependent probe amplification assay for simultaneous detection of six virus species was developed and tested on clinical cerebrospinal fluid (CSF) samples. The assay, termed MeningoFinder, showed an accordance of 97%, concordance of 96%, interlaboratory sensitivity of 90%, and interlaboratory specificity of 94% compared to PCRs. Copyright

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Persistent URL dx.doi.org/10.1128/JCM.02436-08, hdl.handle.net/1765/25243
Citation
Wolffs, P., Vink, C., Keijdener, J., Habek, B., Reijans, M., Simons, G., … van den Brule, A.J.C.. (2009). Evaluation of MeningoFinder, a novel multiplex ligation-dependent probe amplification assay for simultaneous detection of six virus species causing central nervous system infections. Journal of Clinical Microbiology, 47(8), 2620–2622. doi:10.1128/JCM.02436-08