With this prospective observational follow-up study of 165 methicillin-resistant Staphylococcus aureus (MRSA)-positive individuals (23 health care workers and 142 patients), we determined that our MRSA eradication therapy protocol results in a high success rate (81%). Five or more negative culture sets give a predictive value for MRSA eradication therapy success of >90%. Furthermore, MRSA colonization, at least in the throat, and the presence of wounds just before the start of MRSA eradication therapy are associated with MRSA eradication therapy failure. Copyright

doi.org/10.1128/AAC.01240-09, hdl.handle.net/1765/27618
Antimicrobial Agents and Chemotherapy
Erasmus MC: University Medical Center Rotterdam

Mollema, F., Severin, J., Nouwen, J., Ott, A., Verbrugh, H., & Voss, A. (2010). Successful treatment for carriage of methicillin-resistant Staphylococcus aureus and importance of follow-up. Antimicrobial Agents and Chemotherapy, 54(9), 4020–4025. doi:10.1128/AAC.01240-09