Helicobacter Pylori from acquisition to malignancy
H. pylori is known to be the main cause of chronic gastritis, peptic ulcer disease, gastric carcinoma and gastric MALT lymphoma. It is estimated that more than half of the world population is colonized with H. pylori, with the vast majority becoming infected in childhood. The worldwide high prevalence of H. pylori is the reason that gastric cancer remains the fourth most common cancer and second in cancer related deaths. For these reasons epidemiological data on future prevalence, treatment and host genetic factors are needed, as well as data on H. pylori’s most commonly associated diseases and their precursors. These data van be used to draw conclusions on the future burden of H. pylori associated disease and possible screening and surveillance options for subjects at risk of developing gastric cancer.
|Publisher||Erasmus University Rotterdam|
|Promotor||Kuipers, E.J. (Ernst)|
|Sponsor||Erasmus MC afdeling Maag-, Darm- en Leverziekten , Erasmus Universiteit Rotterdam , Mediphos B.V. , Nederlandse Vereniging voor Gastroenterologie , Olympus Nederland B.V.|
den Hoed, C.M.. (2012, June 15). Helicobacter Pylori from acquisition to malignancy. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/32454