Amplified fragment length polymorphism genotypes, antibiotic resistance profiles, and toxin profiles of Clostridium difficile strains from Warsaw were determined. The isolates segregate in six major genotypes, coinciding with toxin profiles. Most of the toxin A-negative toxin B-positive toxin CDT-negative strains possess ermB, and several strains were resistant to fluoroquinolones. Resistograms and toxin types of C. difficile strains are epidemicity determinants. Copyright

doi.org/10.1128/JCM.00306-07, hdl.handle.net/1765/35461
Journal of Clinical Microbiology
Erasmus MC: University Medical Center Rotterdam

Pituch, H., van Leeuwen, W., Maquelin, K., Wultańska, D., Obuch-Woszczatyński, P., Nurzyńska, G., … van Belkum, A. (2007). Toxin profiles and resistances to macrolides and newer fluoroquinolones as epidemicity determinants of clinical isolates of Clostridium difficile from Warsaw, Poland. Journal of Clinical Microbiology, 45(5), 1607–1610. doi:10.1128/JCM.00306-07