Interstitial lung diseases are a heterogeneous group of illnesses with different pathogeneses. In interstitial lung diseases there often is an increased influx of cells from the peripheral blood (PB) to the interstitium and alveoli. Besides the increase in total cell numbers, often marked shifts in the cell populations occur. This thesis describes the immunophenotype of the cells involved in three types of interstitial lung diseases, namely sarcoidosis, idiopathic pulmonary fibrosis (IPF) and extrinsic allergic alveolitis (EM). Emphasis is put on monocytic cells and macrophages. The cell surface markers of monocytes and macrophages as well as the immunophenotype of cultured purified monocytes have been studied. In addition surface antigens of cells from PB and bronchoalveolar lavage (BAL) fluid have been studied in the forementioned interstitial lung diseases

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Erasmus University Rotterdam
C. Hilvering , R. Benner (Robbert)
hdl.handle.net/1765/50783
Erasmus MC: University Medical Center Rotterdam

Hoogsteden, H. (1990, December 19). Heterogeneity of mononuclear phagocytes in interstitial lung diseases. Retrieved from http://hdl.handle.net/1765/50783