1994
The current endothelin receptor classification: Time for reconsideration?
Publication
Publication
Trends in Pharmacological Sciences , Volume 15 - Issue 10 p. 379- 386
The possible involvement of endothelins in a variety of diseases has attracted the attention of many pharmacologists in search of a novel therapeutic approach. The rapid development of endothelin research has resulted in the molecular characterization and pharmacological recognition of ETA and ETB receptors, and in the development of compounds selective for these receptors. However, the characterization of receptors in various assays has shown that a number of effects are mediated by receptors that do not fit the present criteria for ETA or ETB receptors. In this article. Willem Bax and Pramod Saxena address endothelin receptors in general, and atypical receptors in particular.
Additional Metadata | |
---|---|
doi.org/10.1016/0165-6147(94)90159-7, hdl.handle.net/1765/55065 | |
Trends in Pharmacological Sciences | |
Organisation | Department of Pharmacology |
Bax, W., & Saxena, P. R. (1994). The current endothelin receptor classification: Time for reconsideration?. Trends in Pharmacological Sciences (Vol. 15, pp. 379–386). doi:10.1016/0165-6147(94)90159-7 |