On MRI at 35 weeks of a boy born at 25 weeks, focal disorganization of the cortex was observed near a frontal venous infarct developed in the first week. Disruption of the final steps of cell migration, injury to the subplate and/or disruption of corticospinal axons are possible mechanisms behind it. Preterms with white matter lesions at or below 25 weeks postconceptional age should be scrutinized for cortical dysplasia.

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doi.org/10.1016/j.brainres.2006.08.093, hdl.handle.net/1765/61159
Brain Research
Department of Cardiology

Govaert, P., Lequin, M., Korsten, A., Swarte, R., Kroon, A., & Barkovich, J. (2006). Postnatal onset cortical dysplasia associated with infarction of white matter. Brain Research, 1121(1), 250–255. doi:10.1016/j.brainres.2006.08.093