Aortic valve and aortic arch pathology after coarctation repair
OBJECTIVE: To investigate the incidence of clinical problems related to a bicuspid valve (aortic stenosis and regurgitation) and the incidence of ascending aorta and aortic arch pathology in combination with coarctation repair. PATIENTS: 124 adult patients after surgical correction of aortic coarctation were studied. The incidence of aortic valve, ascending aorta, and aortic arch pathology was determined using echocardiography and magnetic resonance imaging. The median age at coarctation repair was 9 years and at last follow up 28 years. RESULTS: Three patients died from aorta pathology. Aortic valve disease was found in 63% of the patients, requiring an intervention in 22%, at a median of 13 years after coarctation repair. Ascending aorta dilatation was observed in 28% and aortic arch abnormalities in 23%, among whom kinking of the aortic arch was found in 12%. Antihypertensive medication was used in 24%. In the patients with hypertension the age at operation and age at follow up were significantly higher (p = 0.0001 and p < 0.0001, respectively). CONCLUSION: In addition to the well known problems of hypertension and recoarctation, aortic valve and aortic arch pathology are commonly encountered in patients with previous coarctation repair. Aortic abnormalities may predispose to dilatation and dissection, thus necessitating careful lifelong attention in all patients with coarctation.
|Keywords||Adolescent, Adult, Aorta, Thoracic, Aortic Coarctation/complications/*surgery, Aortic Valve, Aortic Valve Insufficiency/etiology/mortality/*pathology, Aortic Valve Stenosis/etiology/mortality/*pathology, Child, Child, Preschool, Disease-Free Survival, Female, Humans, Hypertension/complications, Male, Postoperative Complications/etiology/mortality/*pathology, Recurrence, Retrospective Studies|
Roos-Hesselink, J.W., Scholzel, B.E., Heijdra, R.J., Spitaels, S.E.C., Meijboom, F.J., Bogers, A.J.J.C., … Boersma, H.. (2003). Aortic valve and aortic arch pathology after coarctation repair. Heart, 89(9), 1074–1077. Retrieved from http://hdl.handle.net/1765/8335