In a 56-year-old man hypercalcaemia and kidney function impairment were the presenting symptoms of sarcoidosis. The diagnosis was supported by the finding of elevated 1,25-dihydroxyvitamin D levels and of a cluster of epithelioid macrophages in aspirated bone marrow. By exclusion of other granulomatous diseases and a favourable reaction of the hypercalcaemia and renal function to treatment with prednisone the diagnosis was confirmed. The relationship between the autonomous extrarenal production of 1,25-dihydroxyvitamin D and the hypercalcaemia is discussed.

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hdl.handle.net/1765/9131
Nederlands Tijdschrift voor Geneeskunde
Erasmus MC: University Medical Center Rotterdam

Janssen, J., Pols, H., Baggen, M., & Birkenhäger, J. (1989). Hypercalcemia in sarcoidosis. Nederlands Tijdschrift voor Geneeskunde. Retrieved from http://hdl.handle.net/1765/9131