Hypercalcemia in sarcoidosis
In a 56-year-old man hypercalcaemia and kidney function impairment were the presenting symptoms of sarcoidosis. The diagnosis was supported by the finding of elevated 1,25-dihydroxyvitamin D levels and of a cluster of epithelioid macrophages in aspirated bone marrow. By exclusion of other granulomatous diseases and a favourable reaction of the hypercalcaemia and renal function to treatment with prednisone the diagnosis was confirmed. The relationship between the autonomous extrarenal production of 1,25-dihydroxyvitamin D and the hypercalcaemia is discussed.
|Keywords||Calcitriol/blood, Diagnosis, Differential, Hypercalcemia/blood/*etiology, Kidney Diseases/etiology/urine, Prednisone/therapeutic use, Sarcoidosis/*complications/diagnosis/drug therapy, Tuberculosis/diagnosis, humans, male, middle aged|
Janssen, J.A.M.J.L., Pols, H.A.P., Baggen, M.G.A., & Birkenhäger, J.C.. (1989). Hypercalcemia in sarcoidosis. Nederlands Tijdschrift voor Geneeskunde. Retrieved from http://hdl.handle.net/1765/9131