Siezen, C.L.E.

cancer colorectal study fish consumption colorectal cancer colorectal adenomas effect association haplotype consumption n -3 pufas adenomas allele intake interaction genotype pathway tumor nsaid ptgs 2 1.00 colon adenoma control result block polymorphism chapter population pla 2g cancer res factor analysis frequency number n -6 pufas level cyclooxygenase cancer epidemiol.biomarkers prev expression adenoma risk carcinogenesi table colorectal adenoma risk colon cancer sequence aa pathway receptor association studies variant questionnaire nsaid use penetrance alleles case-control study protein tumorigenesi apoptosi colorectal cancer risk candidate disease netherland protein function model enzyme prostaglandin variation tissue fish intake cohort haplotype blocks mouse case-control serum arachidonic penetrance tertile mechanism mutation subject ratio