Pillay, M.

paclitaxel patient plasma concentration cremophor el embolism blood pharmacokinetic sparreboom cancer cremophor fraction disposition study sample dialysis infusion perfusion taxol diagnosis course level equilibrium value strategy perfusion lung scan equilibrium dialysis ratio binding table rotterdam treatment implementation result verweij clearance anticoagulant distribution function phase perfusion scan loos wj paclitaxel fu stoter g metabolite analysis ventilation lung scan g -3h walle experiment paclitaxel disposition curve elimination system nooter stoter excretion nooter k administration dose levels 3- h i.v volume 225 mg /m erythrocyte 6 mg /ml van beek ejr 175 mg /m urine buffer march plasma samples presence verweij j april concentration-time angiography consensus compound serum vehicle