Sprengers, D.

patient hepatitis response infection virus liver hepatitis b t-cell therapy hbv infection study control lamivudine antigen hbv-specific treatment intrahepatic blood hepatitis b virus level hbv patients serum vaccine frequency chapter lymphocytes hbv-dna production interferon phase hbeag analysis antibody dendritic t cells cytokine biopsy replication percentage hepatology responder peg-ifn combination capacity non-responder hepatitis b infection cytotoxic population difference disease function fine-needle aspiration biopsy expression flow cytometry hbv dna result 25+ epitope erasmus mc university immune-clearance phase immunol effect time points il -10 proliferation hla-a virus-specific point staining virus suppression tetramer vivo immunization surface hepatitis b patients cytometry nk cells number factor hbsag -10