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Nawijn, M.C.

(Martijn Nawijn)


expression gata -3 response differentiation development transcription level t cells gata -3 expression t cell development protein figure factor lineage activation thymu 2-gata regulation stage b cells cd 2-gata cd 2-gata mice production receptor thymic socs -3 signal anti-cd t cell differentiation immunol proliferation cytokine spleen population selection phenotype result helper control thymocyte commitment 2 cells 1996. e 41k induction number kinase 1998. activity 1999. culture t cell lineage surface antigen immunity effect maturation 1997. lymph nodes tyrosine presence nature suppression addition btk – background rearrangement lymphoma 2000. domain il -4 analysis family effector mouse cell cycle chapter subset mechanism memory interleukin




6 Most Recent Publications

Suppression of Th2-driven airway inflammation by allergen immunotherapy is independent of B cell and Ig responses in mice (Article)
Shirinbak, S. Taher, Y.A. Nawijn, M.C. Maazi, H. Gras, R. Esch, B.C.A.M. van Henricks, P.A.J. Samsom, J.N. Verbeek, J.S. Lambrecht, B.N.M. Oosterhout, A.J.M. van
2010-10-01
Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice (Article)
Nawijn, M.C. Ferreira, R. Dingjan, G.M. Kahre, O. Drabek, D.D. Karis, A. Hendriks, R.W. Grosveld, F.G.
2001-01-01
Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo (Article)
Nawijn, M.C. Dingjan, G.M. Ferreira, R. Lambrecht, B.N.M. Karis, A. Savelkoul, H.F.J. Hendriks, R.W. Grosveld, F.G.
2001-01-01
Regulation of cell-fate decisions in T lymphocyte differenttiation (Doctoral Thesis)
Nawijn, M.C.
2000-12-06
Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus. (Article)
Hendriks, R.W. Nawijn, M.C. Engel, J.D. Grosveld, F.G. Karis, A. Doorninck, J.H. van
1999-01-01
Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase. (Article)
Dingjan, G.M. Maas, A. Nawijn, M.C. Smit, L. Voerman, J.S. Hendriks, R.W. Grosveld, F.G.
1998-09-15