Panzer-Grumayer, E.R.

patient rearrangement group leukemia lymphoblastic leukemia t-all precursor precursor b-all lymphoblastic level b-all mrd levels igh rearrangements treatment analysis study childhood disease relapse number target point prognostic frequency blood mrd level mrd-based fication infant detection chromosome time points sample signi protocol children oligoclonal interfant mll rearrangements prognostic signi ficance diagnosis outcome velden cazzaniga g van wering prognostic value follow-up t-cell result response van dongen jjm receptor difference interfant -99 protocol figure month value mrd analysis mrd information oligoclonality strati pattern intermediate-risk 5- year rfs pcr targets lymphoblastic leukaemia hyperdiploid mrd-pcr heh leukemias mrd data follow-up time points tel-aml 1 ficance mrd-based risk groups mrd diagnostics mrd negativity allele hyperdiploid b precursor recombination classification