Vuuren, H. van

tfiih activity tfiihmut helicase transcription tfiihwt repair defect fraction antibody patient assay protein subunit atpase reaction mutation purification wild-type erasmus mc control hoeijmaker polypeptide level lanes 3 xpb helicase activity xp 11be bidirectional helicase assay basal dna-dependent kinase basal transcription xpb protein function substrate dna-dependent atpase activities microinjection nucleotide excision repair 0.1 mm edta decrease result deficiency tris-hcl 50 mm tris-hcl factor mother buffer moncollin preparation synthesis erasmu helicase activity ner reaction column xpb gene dna repair xpb polypeptide frameshift mutation weeda cdk 7 ner defect feature www.jbc.org schaeffer terminus bootsma frameshift addition downloaded panel bidirectional vermeulen library domain humbert nucleotide effect atpase activity lymphoblastoid cell line patient xp 11be