Heide, R.

mastocytosi patient cutaneous mastocytosis cutaneou children mast cells urticaria number disease adult treatment tryptase mutation level scorma serum tryptase levels marrow scorma index biopsy urticaria pigmentosa lesion dermatology c-kit symptom serum dermatol study oranje group onset bone marrow diagnosis childhood index oranje ap heide pigmentosa bone marrow biopsy department figure table criteria therapy disorder n-methylhistamine result adult onset mastocytosis blood staining analysis childhood onset mastocytosis netherland rotterdam mediator body sites mastocytose value mast cell accumulation course factor organ classification receptor mast cell mediators atopic dermatitis mast cell skin lesions involvement serum tryptase difference severity allergy method review mastocytoma erasmus mc chapter accumulation mast cell disease valent