Brandel, J-P.

survival disease patient study creutzfeldt –jakob disease onset analysis table control codon creutzfeldt-jakob disease codon 129 exposure creutzfeldt signi mutation prion –jakob factor gender month consumption creutzfeldt-jakob group brain health university iatrogenic animal protein history association department analyses prpsc effect spongiform signi ficance signi ficantly prpsc type germany product surveillance fluence number country finding risk factors spongiform encephalopathy prnp gene italy codon 129 genotype prion protein gene duration reference codon 129 polymorphism polymorphism evidence 14-3-3 model lancet variable neurol neurology transmission crude frequency dementia data collection v 210i patients wilcoxon test epidemiology multivariate 10 years children growth ficantly ficant fi ndings e 200k