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amyloid patient study disease allele control alzheimer mutation apoe -4 allele age-related macular degeneration app 692 mutation protein group apoe -2 allele genet downloaded effect erasmus mc plaque amyloid deposits university dystrophic neurites age-related genet amyloid core population apolipoprotein case-control study arm patients degeneration macular precursor association analysis deposit erasmu arm risk hemorrhage frequency neurite apolipoprotein e brain center neovascular dementia family dystrophic age-related maculopathy genotype 07/28/10 downloaded case-control factor apoe genotypes alzheimer disease vessel drusen erasmus university ophthalmol arm cases jong pt department population stratification j hum genet neuron /vumc neovascular arm lewy bodies apolipoprotein e gene j ophthalmol van duijn cm apoe allele frequencies amyloid precursor protein cortex pittsburgh hchwa-d antibody maculopathy research ophthalmology angiopathy
4 Most Recent Publications
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Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692 Ala => Gly mutation
(Article)
Cras, P. Harskamp, F. van Ceuterick, C. Duijn, C.M. van Stefanko, S.Z. Hofman, A. Kros, J.M. Broeckhoven, C. van Martin, J-J. Hendriks, L. |
1998-09-01
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A population-based study of familial Alzheimer's disease: linkage to chromosome 14, 19 and 21
(Article)
Duijn, C.M. van Hendriks, L. Farrer, L.A. Cruts, M. Wehnert, A. Backhovens, H. Broeckhoven, C. van Hofman, A. |
1994-01-01
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Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β-amyloid precursor protein gene
(Article)
Hendriks, L. Duijn, C.M. van Broeckhoven, C. van Hofman, A. Cras, P. Cruts, M. Hul, W. van Harskamp, F. van Warren, A. McInnis, M.G. Antonarakis, S.E. Martin, J-J. |
1992-01-01
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Amyloid precursor protein gene mutation in early-onset Alzheimer's disease.
(Letter To Editor)
Duijn, C.M. van Cruts, M. Hardy, J. Hendriks, L. Broeckhoven, C. van Hofman, A. |
1991-01-01
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