Boer, A. de

patient study treatment genotype polymorphism therapy stroke pharmacogenetic antihypertensive statin effect antihypertensive drugs result warfarin diuretic dosing coumarin interaction genotyping event group netherland cyp 2c subject vkorc control number disease trial university hypertension response anticoagulation table index date health allele index antipsychotic month coumarin derivatives association difference pharmacy method analysis variant –effectivenes blood factor utrecht population range cost –effectiveness acenocoumarol covariate value effectiveness anticoagulant carrier fracture research dopamine history atrial fibrillation hip /femur fracture fi rst month blood pressure pharmacogenomic pressure ratio outcome future signi pharmo women incidence genotype-guided vkorc 1 level