View Author
disease patient alzheimer mutation polymorphism dementia study family onset association control allele analysis region genotype presenilin psen 1 frequency genet chromosome sequence protein linkage early-onset duijn promoter table intron late-onset alzheimer haplotype late-onset number carrier prion protein gene group lewy body dementia octapeptide insertion marker early-onset alzheimer population neurology cruts m sample 1441c ncstn van duijn cm early-onset ad parkinson 7 q 36 evidence variation amyloid research broeckhoven family history prion department family 1270 linkage disequilibrium rotterdam van duijn alzheimer disease backhovens h individual intron 8 polymorphism population-based hofman netherland rotterdam study locus frontotemporal dementia van broeckhoven c sequencing novel genetic candidate expression population-based study brain
9 Most Recent Publications
|
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease
(Article)
Haugarvoll, K. Rademakers, R. Guidi, M. Riboldazzi, G. Brown, L. Walter, U. Benecke, R. Berg, D. Gasser, T. Theuns, J. Pals, P. Cras, P. Kachergus, J. Deyn, P.P. de Engelborghs, S. Pickut, B. Uitti, R.J. Foroud, T. Nichols, W.C. Hagenah, J. Klein, C. Samii, A. Zabetian, C.P. Nuytemans, K. Bonifati, V. Broeckhoven, C. van Farrer, M.J. Wszolek, Z.K. Ross, O.A. Gibson, J.M. Tan, E.K. Gaig, C. Tolosa, E. Goldwurm, S. |
2008-04-01
|
|
Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample
(Article)
Rijk, P. de Cruts, M. Swieten, J.C. van Aulchenko, Y.S. Rademakers, R. Broeck, M. van den Broeckhoven, C. van Sleegers, K. Dermaut, B. Theuns, J. Weckx, S. Duijn, C.M. van Pooter, T. Corsmit, E. Del-Favero, J. |
2005-01-01
|
|
Familial clustering and genetic risk for dementia in a genetically isolated Dutch population.
(Article)
Sleegers, K. Forey, F. Duijn, C.M. van Broeckhoven, C. van Theuns, J. Aulchenko, Y.S. Rademakers, S. Cruts, M. Gool, W.A. van Heutink, P. Oostra, B.A. Swieten, J.C. van |
2004-07-01
|
|
Octapeptide repeat insertions in the prion protein gene and early onset dementia
(Article)
Croes, E.A. Houwing-Duistermaat, J.J. Sleegers, K. Forey, F. Harten, B. van Cruts, M. Duijn, C.M. van Theuns, J. Swieten, J.C. van Broeckhoven, C. van |
2004-01-01
|
|
The gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample
(Article)
Dermaut, B. Theuns, J. Broeckhoven, C. van Sleegers, K. Hasegawa, H. Vennekens, K. Corsmit, E. St George-Hyslop, P.H. Cruts, M. Duijn, C.M. van Broeck, M. van den |
2002-01-01
|
|
Variable expression of presenilin 1 is not a major determinant of risk for late-onset Alzheimer's Disease
(Article)
Dermaut, B. Roks, G. Breteler, M.M.B. Theuns, J. Rademakers, R. Houwing-Duistermaat, J.J. Serneels, S. Hofman, B. Cruts, M. Broekchoven, C. van Duijn, C.M. van |
2001-11-01
|
|
Genetic variability in the regulatory region of presenilin 1 associated with risk for Alzheimer's disease and variable expression
(Article)
Theuns, J. Del-Favero, J. Dermaut, B. Duijn, C.M. van Serneels, S. Corsmit, E. Cruts, M. Backhovens, H. Broeck, M. van den Broeckhoven, C. van |
2000-01-01
|
|
Genetic association of the presenilin-1 regulatory region with early-onset Alzheimer's disease
(Article)
Duijn, C.M. van Cruts, M. Theuns, J. Gassen, G. van Backhovens, H. Broeck, M. van den Wehnert, A. Serneels, S. Hofman, A. Broeckhoven, C. van |
1999-10-01
|
|
Mapping and sequencing the chromosome 14q24.3 dihydrolipoyl succinyltransferase (DLST) gene in patients with early-onset Alzheimer's disease
(Article)
Cruts, M. Gassen, G. van Broeckhoven, C. van Hofman, A. Theuns, J. Wang, S-Y. Wehnert, A. Duijn, C.M. van Nylander, P-O. Martin, J-J. Adolfsson, R. Backhovens, H. |
1995-01-01
|
