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receptor cancer endometrial estrogen tamoxifen expression growth effect endometrium endometrial cancer factor tibolone progesterone protein egf receptor breast proliferation regulation analysis pathway treatment endometrial cancer cells level ligand result tumor amphiregulin patient study sample presence -36 prab -36 cells breast cancer network igfbp estradiol raloxifene activation tissue group igf 1 women control activity experiment cell lines binding cell line estrogen receptor ici 182780 postmenopausal women transcription response figure profile erasmus univ rotterdam table postmenopausal carcinoma absence invasion process endocrinol growth factor action hormone gynecol igf 1 receptor micro-array cycle insulin-like netherland differentially function gielen gene-expression progestagenic progesterone receptors development
8 Most Recent Publications
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Signaling by estrogens and tamoxifen in the human endometrium
(Article)
Gielen, S.C.J.P. Santegoets, L.A.M. Hanifi-Moghaddam, P. Burger, C.W. Blok, L.J. |
2008-04-01
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Genomic and nongenomic effects of estrogen signaling in human endometrial cells: Involvement of the growth factor receptor signaling downstream AKT pathway
(Article)
Gielen, S.C.J.P. Santegoets, L.A.M. Kühne, L.C. IJcken, W.F.J. van Boers-Sijmons, B. Hanifi-Moghaddam, P. Helmerhorst, T.J.M. Blok, L.J. Burger, C.W. |
2007-10-01
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Estrogen Receptor Signaling in the Endometrium: pathway analysis of agonists and antagonists
(Doctoral Thesis)
Gielen, S.C.J.P. |
2005-11-02
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Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: a putative role for the epidermal growth factor receptor ligand amphiregulin
(Article)
Gielen, S.C.J.P. Burger, C.W. Kühne, L.C. Hanifi-Moghaddam, P. Blok, L.J. |
2005-10-01
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Differences in invasive capacity of endometrial cancer cell lines expressing different progesterone receptor isotypes: possible involvement of cadherins
(Article)
Hanekamp, E.E. Gielen, S.C.J.P. Ruiter, P.E. de Chadha-Ajwani, S. Huikeshoven, F.J. Burger, C.W. Grootegoed, J.A. Blok, L.J. |
2005-05-01
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Molecular portrait of the progestagenic and estrogenic actions of tibolone: behavior of cellular networks in response to tibolone.
(Article)
Hanifi-Moghaddam, P. Gielen, S.C.J.P. Blok, L.J. Kloosterboer, H.J. Gooyer, M.E. de Sijbers, A.M. Gool, A.J. van Smid, M. Moorhouse, M.J. Wijk, F.H. van Burger, C.W. |
2005-02-01
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Progestogenic effects of tibolone on human endometrial cancer cells
(Article)
Blok, L.J. Ruiter, P.E. de Kuhne, E.C. Hanekamp, E.E. Grootegoed, J.A. Smid-Koopman, E. Gielen, S.C.J.P. Gooyer, M.E. de Kloosterboer, H.J. Burger, C.W. |
2003-01-01
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Consequences of loss of progesterone receptor expression in development of invasive endometrial cancer
(Article)
Hanekamp, E.E. Blok, L.J. Huikeshoven, F.J. Gielen, S.C.J.P. Smid-Koopman, E. Kühne, L.C. Ruiter, P.E. de Chadha-Ajwani, S. Brinkmann, A.O. Grootegoed, J.A. Burger, C.W. |
2003-01-01
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