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patient study lamotrigine treatment tumor bipolar phase cancer placebo group depression sertoli bipolar depression lithium level breast paroxetine sertoli cells factor receptor activin addition breast cancer tamoxifen adam -9 e fficacy expression result response protein therapy inhibin psychiatry score disease medium control disorder fisher month androgen -11 fficacy adam -11 trial tamoxifen therapy follow-up fi rst phase cgi-bp responder growth netherland outcome signi table baseline di fference culture effect activin-a analysis madrs score bipolar disorder assay e ffective animal library erasmus mc disease control bipolar i disorder phase 1 value progression-free survival change rat sertoli cells tm 4 cells lamlit study group nuclei non-responder sample t-test
5 Most Recent Publications
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Long-term outcome of bipolar depressed patients receiving lamotrigine as add-on to lithium with the possibility of the addition of paroxetine in nonresponders: A randomized, placebo-controlled trial with a novel design
(Article)
Loos, M.L.M. van der Mulder, P. Hartong, E.G.Th.M. Blom, M.B.J. Vergouwen, A.C. Noorden, M.S. van Timmermans, M.A. Vieta, E. Nolen, W.A. |
2011-02-01
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Efficacy and safety of two treatment algorithms in bipolar depression consisting of a combination of lithium, lamotrigine or placebo and paroxetine
(Article)
Loos, M.L.M. van der Mulder, P.G.H. Hartong, E.G.Th.M. Blom, M.B.J. Vergouwen, A.C. Noorden, M.S. van Timmermans, M.A. Vieta, E. Nolen, W.A. |
2010-09-01
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Efficacy and safety of lamotrigine as add-on treatment to lithium in bipolar depression: A multicenter, double-blind, placebo-controlled trial
(Article)
Loos, M.J.H.M. van der Mulder, P.G.H. Nolen, W.A. Hartong, E.G.Th.M. Blom, M.B.J. Vergouwen, A.C. Keyzer, H.J.U.E.M. de Notten, P.J.H. Luteijn, M. Timmermans, M.A. Vieta, E. |
2009-02-01
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How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study.
(Article)
Sieuwerts, A.M. Meijer van Gelder, M.E. Timmermans, M.A. Trapman, A.M. Garcia, R.R. Arnold, M. Goedheer, A.J. Portengen, H. Klijn, J.G.M. Foekens, J.A. |
2005-10-15
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Activin is produced by rat Sertoli cells in vitro and can act as an autocrine regulator of Sertoli cell function
(Article)
Winter, J.P. de Vanderstichele, H.M.J. Timmermans, M.A. Blok, L.J. Themmen, A.P.N. Jong, F.H. de |
1993-01-01
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