Kasteren, J.H.

patient gr gene cortisol receptor glucocorticoid resistance level analysis cell dex-binding assay concentration hormone-binding domain cortisol suppression library erasmus mc syndrome cushing alteration polymorphism cortisol resistance mutation suppression pcr /sscp analysis domain glucocorticoid receptor gene endocrinol glucocorticoid resistance coding part assay metab symptom number study glucocorticoid receptor sequence analysis binding asthma j clin family hormone-binding sequence cortisol concentrations gr gene alterations mitogen-induced proliferation assay blood leukocyte serum mitogen-induced cell proliferation 1- mg dst androgen proliferation /sscp serum cortisol concentrations mitogen-induced 1- mg respect coding koper overproduction cortisol excretion sensitivity clinic affinity steroid-resistant asthma disease fatigue effect rhythm hirsutism dex-binding protein lambert complaint family members diagnosis response circadian rhythm member rev respir dis huizenga patient 5 gr protein