Bonifati, V.

mutation disease patient parkinson family study parkin parkinsonism protein onset disorder analysis neurol neurology parkin gene control region parkin mutations population brain linkage recessive autosomal variant genet chromosome movement early-onset subject locus tremor group frequency lrrk 2 mutations result bonifati lewy bodies lrrk 2 deletion carrier parkinson disease dystonia table haplotype syndrome cause bonifati v department factor evidence phenotype motor marker university association genetic effect feature alpha-synuclein synuclein symptom identi chapter disord allele parkin gene mutations activity response lrrk 2 gene movement disorders function score 2019ser autosomal recessive sample research pd patients system neuron expression