Bruijn, M.J.W. de

(Marjolein de Bruijn)

expression gata 3 cd 2-gata gata 3 expression 2-gata pre-b figure level development analysis leukemia differentiation immunol b cells transcription tumor b-cell factor thymocyte dp cells chain c-myc protein wild-type number pre-b cells lymphoma cd 19-hbtk mice ﬁcient selection lineage region recombination locus cd 2–gata mice receptor transformation result flow cytometric analysis gata -3 expression 17 cells presence arthritis cd 2-gata transgene nding transgene igk locus induction cytokine 19-hbtk il -4 stage gata -3 11.10 blood notch mouse t cell development group speci erasmus mc effect -17 17 differentiation fraction culture cd 4 lineage igh.te kinase slp 65 control signi ﬁ nding 65-de interaction 17 cultures segment 1-cre rt-pcr 65ϫ/ϫ

10 Most Recent Publications

Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice (Article) Kil, L. Bruijn, M.J.W. de Loo, P.F. van Hendriks, R.W. Nimwegen, M. van Corneth, O.B.J. Hamburg, J.P. van Dingjan, G.M. Thaiss, F. Rimmelzwaan, G.F. Elewaut, D. Delsing, D.	2012-04-19
The DNA-Binding Protein CTCF Limits Proximal Vκ Recombination and Restricts κ Enhancer Interactions to the Immunoglobulin κ Light Chain Locus (Article) Ribeiro de Almeida, C. Stadhouders, R. Hendriks, R.W. Bruijn, M.J.W. de Bergen, I.M. Thongjuea, S. Lenhard, B. IJcken, W.F.J. van Grosveld, F.G. Galjart, N. Soler, E.	2011-10-28
Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity (Article) Ta, T.B.V. Haan, A.B. Bruijn, M.J.W. de Dingjan, G.M. Hendriks, R.W.	2010-10-29
Malignant transformation of Slp65-deficient pre-B cells involves disruption of the Arf-Mdm2-p53 tumor suppressor pathway (Article) Ta, T.B.V. Bruijn, M.J.W. de Brugge, P.J. ter Hamburg, J.P. van Diepstraten, H.J.A. Loo, P.F. van Kersseboom, R. Hendriks, R.W.	2010-02-18
A mouse model for chronic lymphocytic leukemia based on expression of the SV40 large T antigen (Article) Brugge, P.J. ter Ta, T.B.V. Bruijn, M.J.W. de Keijzers, G. Maas, A. Gent, D.C. van Hendriks, R.W.	2009-11-18
Gene expression profiling in mice with enforced Gata3 expression reveals putative targets of Gata3 in double positive thymocytes (Article) Hamburg, J.P.v. Bruijn, M.J.W. de Ribeiro de Almeida, C. Dingjan, G.M. Hendriks, R.W.	2009-10-01
GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis (Article) Hamburg, J.P. van Mus, A.M. Bruijn, M.J.W. de Vogel, L. de Boon, L. Cornelissen, F.H.J. Asmawidjaja, P. Hendriks, R.W. Lubberts, E.W.	2009-03-01
Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology (Article) Hamburg, J.P. van Bruijn, M.J.W. de Ribeiro de Almeida, C. Zwam, M. van Meurs, M. van Haas, E.F. de Boon, L. Samsom, J.N. Hendriks, R.W.	2008-09-01
Cooperation of Gata3, c-Myc and Notch in malignant transformation of double positive thymocytes (Article) Hamburg, J.P. van Bruijn, M.J.W. de Dingjan, G.M. Beverloo, H.B. Diepstraten, H.J.A. Ling, K-W. Hendriks, R.W.	2008-06-01
GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development (Article) Ling, K-W. Hamburg, J.P. van Bruijn, M.J.W. de Kurek, D.M. Dingjan, G.M. Hendriks, R.W.	2007-04-01

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