Ebus, M.E.

ara-c infant expression patient children leukemia mrna expression sample mll generearranged ara-ctp ara-c sensitivity sensitivity lymphoblastic leukemia mll gene rearrangements generearranged group leukemic dck mrna expression cytosine arabinoside deoxycytidine enzyme resistance blood value dcmpd level figure kinase leukemic cells deaminase nucleoside cytosine lymphoblastic treatment oligonucleotide microarray screen number study deoxycytidine kinase arabinoside membrane ara-cmp rearrangement hent 1 mrna difference gibco brl mrna expression levels transporter microarray taqman transport minute probe hent 1 ara-cmetabolizing enzymes oligonucleotide cytidine life technologies lc 50 values cytotoxic form ara-ctp volume netherland mll generearranged infant deoxycytidylate deaminase ara-c cytotoxicity cytidine deaminase technology concentration hospital cell membrane cancer dck mrna screen 12 months assay treatment protocol protocol gapdh cytotoxicity phosphorylated pyrimidine