Opstal, A.R.M. van

chromosome probe trisomy mosaicism result analysis embryo diagnosis hybridization karyotype study cytogenetic genet mosaic sample signal abnormality marker chromosomal pregnancy culture nuclei chorionic fetus origin aberration syndrome diagn detection preparation table parent villi uncultured level fluid j med genet placental slide villu interphase ofthe prei /at diagn chorionic villi sampling region disomy opstal figure number technique deletion blastomere zygote patient placenta trisomic uniparental kalousek ultrasound method prenat investigation semi-direct fish results placental mosaicism af cells fluorescence van opstal anomaly uniparental disomy presence metaphase series chromosome aberrations follow-up diagil publication tissue trimester