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Lohuizen, M. van

( M. van Lohuizen)


figure expression hoxa 9 globin bmi 1 protein locus b globin locus chromatin result control number level effect 16ink b globin gene p 16ink -/- cell bmi 1 concentration background hematopoietic region senescence dnase colony transduced transformation promoter change assay hox genes suv 39h maf 9 leukemia drosophila fusion hox crosstalk transcriptional round establishment dnase i sensitivity bmi 1à/à cells transgene absence self-renewal bm cells transduced eklf +/± background factor wild-type 1à/àhoxa analysis centromeric scale bar increase meis 1 vector chromatin structure cdkn 2a locus development mouse ¯uence bmi 1à/àhoxa mice function mll fusions decrease immunophenotype leukemic 5¢- position bmi 1. ¯uence pev satellite transcription defect pc-g proteins chromatin ® bres cancer cell surface markers antibodies speci fic




2 Most Recent Publications

Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells (Article)
Smith, L.L. Yeung, J. Lohuizen, M. van So, C.W.E. Zeisig, B.B. Popov, N. Huijbers, I. Barnes, J. Wilson, A.J. Taskesen, E. Delwel, H.R. Gil, J.
2011-06-03
Activation of the beta β globin locus by transcription factors and chromatin modifiers. (Article)
McMorrow, T. Wijngaard, A. van den Trimborn, T. Lohuizen, M. van Jenuwein, T. Djabali, M. Philipsen, J.N.J. Fraser, P. Grosveld, F.G. Milot, E.
2000-01-01