Bie, M. de

cmc -544 rearrangement -544 leukemia cd 22 expression ef ficacy calicheamicin expression ficacy precursor-ball patient lymphoblastic leukemia van dongen jjm bcp-all figure internalization analysis segment lymphoblastic level sensitivity receptor bcp-all cells blood ic 50 values target 37 1 c clonal cmc -544. childhood concentration death t-cell b-cell disease study cell lines dongen germline saturation relapse sample cd 22 ags intracellular detection value antibody j segments aml cells ozogamicin -544. bcp-all jf binding cd 22 van wering sequence gemtuzumab ozogamicin joining diagnosis incubation region szczepanski wolvers-tettero ilm treatment junctional cell survival intracellular accumulation target cells recombination primers rq-pcr cd 33 ags cd 22 ratio -544-induced survival primer gemtuzumab myeloid leukemia cell surface calicheamicin sensitivity