Jacobs, D.C.

rearrangement precursor-ball van dongen jjm leukemia segment lymphoblastic leukemia analysis clonal receptor lymphoblastic t-cell disease blood dongen germline relapse sample detection j segments childhood van wering sequence joining diagnosis region szczepanski wolvers-tettero ilm junctional target recombination primers rq-pcr primer figure lymphoid level usage presence junctional regions tissue delta number mrd-pcr targets germline v 2 br j haematol product precursor heteroduplex probe pcr targets immunoglobulin rq-pcr analysis wering willemse mj lymphoblastic leukaemia lymphoid tissues b-cell precursors frequency thymu sequence analysis lymphoid cells b-cell multiplex szczepanski t wolvers-tettero tcrd /a locus v 2 primer tcrd gene rearrangements adult clonal pcr products clonal v 2- patient 2- j rearrangements heteroduplex pcr analysis j gene segments oligoclonal deletion cluster precursor-b taqman