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diabetes study type 2 diabetes mitochondrial sample association variant control netherland center university h 324q replication participant lars 2 cohort result dutch research glucose table allele protein analysis meta-analysi lars 2 gene susceptibility hoorn study t 2dm evidence genotyping stage genet health subject hoorn leiden university power patient denmark steno diabetes center population leiden mitochondrial protein synthesis genome-wide department polymorphism genetic disease frequency diagram mellitu european type 2 science nl 1 sample mutation allele frequency synthesis allele frequencies region difference variation nuclear-encoded steno consortium odds ratio research centre lars 2 locus t 2dm susceptibility h 324q variant sirt 4 ratio diabetes mellitus diabetologia insulin enzyme function synthetase replication samples
3 Most Recent Publications
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Genetic association analysis of LARS2 with type 2 diabetes
(Article)
Reiling, E. Jafar-Mohammadi, B. Nijpels, M.G.A.A.M. Groenewoud, M.J. Hove, E.C. van Uitterlinden, A.G. Smit, J.W.A. Morris, A.D. Doney, A.S.F. Palmer, C.N.A. Guiducci, C. Hattersley, A.T. Riet, E. van 't Frayling, T.M. Pedersen, O. Slagboom, P.E. Altshuler, D. Groop, L. Romijn, J.A. Maassen, J.A. Hofker, M.A. Dekker, J.M. McCarthy, M.I. Weedon, M.N. Hart, L.M. 't Vliet-Ostaptchouk, J.V. van Hansen, T. Saxena, R. Haeften, T.W. van Arp, P.P. Das, S. |
2010-01-01
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Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study
(Article)
Reiling, E. Vliet-Ostaptchouk, J.V. van Smit, J.W.A. Nijpels, M.G.A.A.M. Heine, R.J. Uitterlinden, A.G. Pedersen, O. Slagboom, P.E. Maassen, J.A. Hofker, M.A. Hart, L.M. 't Dekker, J.M. Riet, E. van 't Haeften, T.W. van Arp, P.P. Hansen, T. Kremer, D. Groenewoud, M.J. Hove, E.C. van Romijn, J.A. |
2009-02-12
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Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene
(Article)
Hart, L.M. 't Pols, H.A.P. Uitterlinden, A.G. Jorgensen, T. Duijn, C.M. van Borch-Johnsen, K. Pedersen, O. Hansen, T. Rietveld, I. Dekker, J.M. Maassen, J.A. Nijpels, M.G.A.A.M. Janssen, G.M. Arp, P.P. Heine, R.J. |
2005-01-01
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