Hatanaka, H.

xpa ϫ/ϫcsb mice ϫ/ϫcsb ϩ/ϫcsb xpa ϩ/ϫcsb cerebellar xpa ϫ/ϫcsb cerebellum postnatal xpa ϩ/ϫcsb mice repair layer defect abnormality development animal control patient genotype tunel-positive cells mouse p 14. values xpa ϫ/ϫcsb animals system brain lobule comparison apoptosi phenotype neurogenesi csb gene defects nucleotide excision repair result hoeijmaker apoptotic cell death number n ϭ 6 xpa ϫ/ϫcsb cerebellum lobules i ͞ii damage protein postnatal development exhibit contrast section dendritic symptom tunel-positive dysfunction growth murai birth death oxidative dna damage cs patients retardation postnatal stage lesion transcription granule cell layer display fi ve mice excision neurosci autosomal recessive disorders 98 ͉ reduction ataxia cockayne syndrome cancer ͞or cs-b patients ix ͞x proliferation n ϭ 7 mouse models pc layer xpa ؊/؊csb cerebellum csb gene products growth retardation xp patients postnatal life