Broecke, D.G. van den

hidradenitis suppurativa control control skin suppurativa hidradeniti il -10 signi ficantly tnf-a -10 level cytokine il -1b hs skin il -1b tnf-a flammatory signi hurley disease ficantly patient psoriasis van der zee phs skin biopsy perilesional study lesional detection limit sample il -10 levels dermatol lhs skin result culture flammation lesion necrosis biologic lesional hidradenitis suppurativa anti-tnf-a biologics hidradenitis suppurativa skin 40 lhs samples il -10 production treatment cytokine levels interleukin weight flammasome macrophage perilesional hs skin tumour acta derm venereol hs lesions limit ef ficacy disease severity british detection factor 1292–1298 anti-tnf-a author severity abscess tissue dermatologist stage punch surgery association *** 0·1 jemec gb log scale hurley classi fication flamed psoriatic skin bd biosciences culture medium punch biopsies