Verhoog, L.C.

cancer breast breast cancer mutation patient family brca 1 women tumor study breast cancer patients carrier prophylactic survival mastectomy prophylactic mastectomy group brca 2 mutation recurrence brcaj brca 2 mutations brca 2 diagnosis result contralateral breast cancer therapy analysis number family history surveillance factor characteristic genet difference status contralateral follow-up testing carcinoma germline susceptibility prophylactic surgery control surgery prognostic j hum genet breast cancer risk table history 1/2 brcai ipsilateral founder oophorectomy disease incidence population ipsilateral recurrence syndrome receptor linkage br j cancer outcome family cancer clinic clinic dna testing breast cancers seynaeve c screening klijn verhoog brca 1 mutations van den ouweland borstkanker lancet brca 2 genes klijn jg protein ct al 50 years