Rijk, P. de

family patient disease 7 q 36 family 1270 linkage alzheimer allele mutation duijn marker analysis haplotype van duijn early-onset ad region individual onset number study paxip dementia early-onset table sequence candidate region cruts m van duijn cm broeckhoven control alzheimer disease paxip 1 hofman candidate dutch sample frequency proband 80- bp allele genet van broeckhoven c association genetic genotype american journal backhovens h protein g .38030grc range genotype data multiplex ad family 1270. flanders interuniversity institute locus population-based dermaut van den bm pedigree age 65 years dutch patient-control sample score autosomal age 82 years diagnosis center symbol chromosome early-onset alzheimer late-onset figure report coding exons population-based study mutation analysis disease haplotype coding breteler mm .38030grc earlyonset ad 1994 b