Clayton, R.N.

gh 3 cells tumor receptor patient gr gene study expression apoptotic polymorphism challenge gr gene locus mmq cells cortisol response histone gh 3-d cells adenomas cortisol resistance apoptosi mutation zebularine resistance leukocyte glucocorticoid analysis experiment cancer 2r expression exon v point antagonist corticotropinoma tumor dna methylation apoptotic response drug challenges gh 3-d pattern cushing locus endocrinol treatment effect island 22 patients dopamine enrichment cell line cell lines leukocyte dna library erasmus mc agonist specificity pathway modification agent histone modifications cpg island glucocorticoid resistance disease reexpression control endocrinology syndrome apoptotic end points glucocorticoid receptor subject absence metab adenoma sirna inhibitor fragment feedback bc challenges –373 chromosome demethylation tumor types feedback action