Down, J.D.

marrow compound activity pl 63 transplantation analogue engraftment study spleen busulfan treatment donor bone marrow transplantation hematopoietic level hepsulfam group transplant assay bu analogues effect 5/5 distance treosulfan depletion cancer conditioning ability cafc assay cell subsets survival chimerism blood 300 mg /kg donor marrow engraftment value allogeneic subset murine pharmacokinetic syngeneic table leukemia 3/3 hematopoiesi property liver toxicity alkylating patient partition coefficients irradiation alkylating groups rapamycin body irradiation internucleophile distances animal concentration cyclic coefficient syngeneic bmt myeloid leukemia control ploemacher aliphatic therapy 4/4 partition internucleophile sample bone marrow chimerism cyclophosphamide 50 mg /kg frequency bmt conditioning therapy 150 mg /kg bone marrow cells correlation cyclohexane pharmacokinetic properties