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Wognum, B.W.
( B.W. Wognum)
patient effect cytogenetic response leukemia cytogenetic response culture stromal progenitors progenitor interferon study production progenitor cells flask ltc percentage hematopoietic myeloid myeloid leukemia cml progenitors flask blood ph nc concentration stromal cell line control nonresponding patients presence result frequency nonresponder inhibition marrow sample signal assay diagnosis analysis responder cobblestone leukemic ploemacher antiproliferative cd 34 table cytogenetic conversion cml patients slide stromal cells hematopoietic progenitor cells clonogenic chromosome cd 34 cells number outgrowth metaphase survival stromal layers cfu-gm finding layer growth stromal feeders nonresponding adhesion cornelissen cfu-c murine hybridization treatment cycle nonadherent addition granulocyte range dilution activity difference factor bfu-e
1 Most Recent Publications
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An in vitro model for cytogenetic conversion in CML. Interferon-alpha preferentially inhibits the outgrowth of malignant stem cells preserved in long-term culture
(Article)
Cornelissen, J.J. Ploemacher, R.E. Wognum, B.W. Borsboom, A. Kluin-Nelemans, H.C. Hagemeijer, A. Löwenberg, B. |
1998-01-01
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