Rippe, K.

histone chromatin image analysis acetylation histone acetylation cycle concentration control effect intensity cell cycle stage protein 24 hours distribution uorescence change decondensation apoptosi correlation deacetylase length image correlation spectroscopy cell cycle progression binding chromatin fi ber signi phase stage structure expression region inhibitor function incubation cell biol tsa treatment pixel treatment increase trichostatin hansen value conformation tsa-induced arrest nuclei facs analysis histone tails fication tsa-treated cells dna content cancer scale yoshida control cells difference dimension nucleosome heidelberg interphase fractal density 12 hours image analysis nucleus tsa concentrations fractal dimension cell cycle correlation length 4 hours method gene expression signi ficantly apoptotic cells minute ficant tsa concentration germany tsa-treated