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expression development factor sox 2 diaphragmatic hernia protein lung development control level mouse airway study pediatr model transgene diaphragmatic differentiation hypertension hernia wnt 5a ea /tef vessel result epithelium defect pathway epithelial receptor morphogenesi import number syndrome patient stage transcription growth lcr-g tissue wnt 5a expression staining mutation formation animal gata 1 erythroid chd 7 exp 4 embryo lesion epithelial cells analysis effect adult anomaly blood intestine foregut mechanism vasculature artery animal models abnormality infant speci treatment adenomatoid malformation explant research process review atresia regulation figure disease sox 2 expression genet physiol diaphragm promoter induction
10 Most Recent Publications
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Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice
(Article)
Bakker, E.R.M. Raghoebir, L.J Smits, R. Franken, P.F. Helvensteijn, W. Gurp, L. van Meijlink, F. Valk, M. van der Rottier, R. Kuipers, E.J. Veelen, W. van |
2012-09-01
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Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
(Article)
Engelen, E. Akinci, U. Demmers, J.A. Rijkers, E.J. Bhattacharya, S. Philipsen, S. Pevny, L.H. Grosveld, F.G. Rottier, R. Lenhard, B. Poot, R.A. Bryne, J.C. Hou, J. Gontan, C. Moen, M.H. Szumska, D. Kockx, C. IJcken, W.F.J. van Dekkers, D.H. |
2011-06-01
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Vascular abnormalities in human newborns with pulmonary hypertension
(Article)
Sluiter, I. Reiss, I.K.M. Kraemer, U. Krijger, R.D. Tibboel, D. Rottier, R. |
2011-04-01
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Congenital lung lesions-underlying molecular mechanisms
(Article)
Correia-Pinto, J. Gonzaga, S. Huang, Y. Rottier, R. |
2010-08-01
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Effect of oxygen on the expression of hypoxia-inducible factors in human fetal lung explants
(Article)
Rajatapiti, P. Rooij, J.D. de Beurskens, L.W.J.E. Keijzer, R. Tibboel, D. Rottier, R. Krijger, R.R. de |
2010-06-01
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Congenital lung lesions-underlying molecular mechanisms
(Article)
Correia-Pinto, J. Gonzaga, S. Huang, Y. Rottier, R. |
2010-01-01
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Genetic and environmental factors in the etiology of esophageal atresia and/or tracheoesophageal fistula: An overview of the current concepts
(Article)
Felix, J.F. Jong, E.M. de Torfs, C.P. Klein, J.E.M.M. de Rottier, R. Tibboel, D. |
2009-09-01
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Can we improve outcome of congenital diaphragmatic hernia?
(Article)
Hout, L. van den Sluiter, I. Gischler, S.J. Klein, J.E.M.M. de Rottier, R. IJsselstijn, H. Reiss, I.K.M. Tibboel, D. |
2009-09-01
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Generation of a tightly regulated doxycycline-inducible model for studying mouse intestinal biology
(Article)
Roth, S. Franken, P.F. Smits, R. Veelen, W. van Blonden, L. Raghoebir, L.J Beverloo, H.B. Drunen, E. van Kuipers, E.J. Rottier, R. Fodde, R. |
2009-07-01
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Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors
(Article)
Gontan, C. Guttler, T. Engelen, E. Demmers, J.A. Fornerod, M.W.J. Grosveld, F.G. Tibboel, D. Görlich, D. Poot, R.A. Rottier, R. |
2009-04-06
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