Strous, G.J.

catenin β- catenin dephosphorylated β- catenin β- catenin levels transcription level increase dephosphorylated tcf-dependent transcription 33 β- catenin 293 t cells signal treatment wnt signals figure activity phosphorylation tcf-mediated transcription antibody reporter transfection protein wnt 1 amount accumulation report phosphorylated β- catenin pathway alln treatment tcf-dependent 3 | ts 20 cells wnt 1 transfection licl treatment transfected factor ubiquitylation phosphorylation status result temperature β- catenin degradation mutation β- catenin half-life activation β- trcp 2 gumbiner xenopus embryos half-life event f-box inhibition kinase tcf-mediated phosphorylated study peifer staal degradation figure 2 effect 33 β catenin transduction control α abc proteasome inhibitor alln clever β- trcp reporter gene figure 1 b report f.j.t 40° c contrast xenopu reporter gene activity β- catenin breakdown wingles wg /wnt miller drosophila gsk -3β