Ploeg, H.

adenosine adenosine receptors receptor preconditioning mao 15 cardioprotection artery neurogenic pathway adenosine receptor stimulation heart infarct size ischemia 8- spt mao-p infarct group reperfusion physiol intestine 60- min cao protection neurogenic pathway ischemic 5 min infusion ado ima stimulation ischemic preconditioning intramesenteric artery infusion involvement effect hexamethonium artery reperfusion animal action study occlusion protocol mao 15. myocardium interorgan activation pretreatment 15. portal vein nerve collateral stimulus intramesenteric blood duncker verdouw pd duncker dj interorgan preconditioning 60- 3- cao 3 van den doel 3- mao 3 0.05 interorgan preconditioning fig antagonist adenosine receptor blockade cardioprotective kloner ra cao 15 www.ajpheart.org circulation adenosine concentrations iopc stimulus ajp-heart observation portal concentration 2001. 1999. result blockade verdouw ischemic organ