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    <title>Klazinga, N.S.</title>
    <link>http://repub.eur.nl/res/aut/15286/</link>
    <description>List of Publications</description>
    <language>en</language>
    <image>
      <url>http://repub.eur.nl/static-eur/img/logo.png</url>
      <title>RePub, Erasmus University Rotterdam</title>
      <link>http://repub.eur.nl</link>
    </image>
    <item>
      <title>Why a successful task substitution in glaucoma care could not be transferred from a hospital setting to a primary care setting: A qualitative study (Article)</title>
      <link>http://repub.eur.nl/res/pub/39834/</link>
      <pubDate>2013-01-25T00:00:00Z</pubDate>
      <description>Background: Healthcare systems are challenged by a demand that exceeds available resources. One policy to meet this challenge is task substitution-transferring tasks to other professions and settings. Our study aimed to explore stakeholders' perceived feasibility of transferring hospital-based monitoring of stable glaucoma patients to primary care optometrists.Methods: A case study was undertaken in the Rotterdam Eye Hospital (REH) using semi-structured interviews and document reviews. They were inductively analysed using three implementation related theoretical perspectives: sociological theories on professionalism, management theories, and applied political analysis.Results: Currently it is not feasible to use primary care optometrists as substitutes for optometrists and ophthalmic technicians working in a hospital-based glaucoma follow-up unit (GFU). Respondents' narratives revealed that: the glaucoma specialists' sense of urgency for task substitution outside the hospital diminished after establishing a GFU that satisfied their professionalization needs; the return on investments were unclear; and reluctant key stakeholders with strong power positions blocked implementation. The window of opportunity that existed for task substitution in person and setting in 1999 closed with the institutionalization of the GFU.Conclusions: Transferring the monitoring of stable glaucoma patients to primary care optometrists in Rotterdam did not seem feasible. The main reasons were the lack of agreement on professional boundaries and work domains, the institutionalization of the GFU in the REH, and the absence of an appropriate reimbursement system. Policy makers considering substituting tasks to other professionals should carefully think about the implementation process, especially in a two-step implementation process (substitution in person and in setting) such as this case. Involving the substituting professionals early on to ensure all stakeholders see the change as a normal step in the professionalization of the substituting professionals is essential, as is implementing the task substitution within the window of opportunity. </description>
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      <title>Hospital benchmarking: Are U.S. eye hospitals ready? (Article)</title>
      <link>http://repub.eur.nl/res/pub/26339/</link>
      <pubDate>2012-04-01T00:00:00Z</pubDate>
      <description>Background: Benchmarking is increasingly considered a useful management instrument to improve quality in health care, but little is known about its applicability in hospital settings. Purpose: The aims of this study were to assess the applicability of a benchmarking project in U.S. eye hospitals and compare the results with an international initiative. Methodology: We evaluated multiple cases by applying an evaluation frame abstracted from the literature to five U.S. eye hospitals that used a set of 10 indicators for efficiency benchmarking. Qualitative analysis entailed 46 semistructured face-to-face interviews with stakeholders, document analyses, and questionnaires. Findings: The case studies only partially met the conditions of the evaluation frame. Although learning and quality improvement were stated as overall purposes, the benchmarking initiative was at first focused on efficiency only. No ophthalmic outcomes were included, and clinicians were skeptical about their reporting relevance and disclosure. However, in contrast with earlier findings in international eye hospitals, all U.S. hospitals worked with internal indicators that were integrated in their performance management systems and supported benchmarking. Benchmarking can support performance management in individual hospitals. Having a certain number of comparable institutes provide similar services in a noncompetitive milieu seems to lay fertile ground for benchmarking. International benchmarking is useful only when these conditions are not met nationally. Practice Implications: Although the literature focuses on static conditions for effective benchmarking, our case studies show that it is a highly iterative and learning process. The journey of benchmarking seems to be more important than the destination. Improving patient value (health outcomes per unit of cost) requires, however, an integrative perspective where clinicians and administrators closely cooperate on both quality and efficiency issues. If these worlds do not share such a relationship, the added "public" value of benchmarking in health care is questionable. Copyright </description>
    </item> <item>
      <title>Veiliger zorg door vliegveldmarkering in operatiekamer (Article)</title>
      <link>http://repub.eur.nl/res/pub/37200/</link>
      <pubDate>2012-01-01T00:00:00Z</pubDate>
      <description>Design van de werkomgeving heeft een belangrijke invloed op menselijk
gedrag. In dit artikel wordt betoogd hoe het aanbrengen van
vloermarkering in de operatiekamers van Het Oogziekenhuis Rotterdam
leidde tot een betere positionering van materialen en mensen.
Hoe een simpele lijn op de grond tot veiliger zorgverlening leidt.</description>
    </item> <item>
      <title>Safety by design: effects of operating room floor marking on the position of surgical devices to promote clean air flow compliance and minimise infection risks (Article)</title>
      <link>http://repub.eur.nl/res/pub/37219/</link>
      <pubDate>2012-01-01T00:00:00Z</pubDate>
      <description>Objective: To evaluate the use of floor marking on the
positioning of surgical devices within the clean air flow
in an operating room (OR) to minimise infection risk.
Laminar flow clean air systems are important in
preventing infection in ORs but, for optimal results,
surgical devices must be correctly positioned.
Methods: The authors evaluated floor marking in four
ORs at an eye hospital using time series analysis.
Through observations during 829 surgeries over a 20-
month period, the positions of surgical devices were
determined. Eight semistructured interviews with
surgical staff were conducted to assess user
experiences and team dynamics.
Results: Before marking, the instrument table was
positioned completely within the laminar flow in only
6.1% of the cases. This increased to 36.1% and finally
53.8%. Mayo stands were increasingly positioned
within the laminar flow: from 74.2% to 84.7%. The
surgical lamp decreasingly obstructed flow: from
41.8% to 28.7%. At T3 (20 months), however, in
48.6% of the applicable cases the lamp was positioned
in the flow again. Discussions and site visits between
airside operators and surgical staff resulted in
increasing awareness of specific risk areas in the OR.
Conclusions: OR floor markings facilitated and
stimulated safety awareness and resulted in
significantly increased compliance with the positioning
of surgical devices in the clean air flow. Safety and
quality approaches in hospital care, therefore, should
include a human factors approach that focuses on
system design in addition to teaching clinical and nontechnical
skills.
</description>
    </item> <item>
      <title>Health services research related to performance indicators and benchmarking in Europe (Article)</title>
      <link>http://repub.eur.nl/res/pub/34303/</link>
      <pubDate>2011-07-01T00:00:00Z</pubDate>
      <description>Objective: Measuring quality of care through performance indicators and subsequently using these to compare, learn, and improve (benchmarking) has become a central component of health care policy. This paper aims to identify the main themes of health services research in this area and focuses on opportunities for improving the evidence underpinning performance indicators. Methods: A literature survey was carried out to identify research activities and main research themes in Europe in the years 2000-09. Identified literature was categorized into sub-topics and for each topic the main methodological issues were identified and discussed. Experts validated the findings and explored the potential for related further European research. Results: The distribution of research on performance and benchmarking across EU member states varies in time, scope and settings with a large amount of studies focusing on hospitals. Eight specific fields of research were identified (research on concepts and performance frameworks; performance indicators and benchmarking using mortality data; performance indicators and benchmarking related to cancer care; performance indicators and benchmarking on care delivered in hospitals; patient safety indicators; performance indicators in primary care; patient experience; research on the practice of benchmarking and performance improvement). Expert discussions confirmed that research on performance indicators and benchmarking should focus on the development of indicators, as well as their use. The research should involve the potential users and incorporate scientific approaches from biomedicine and epidemiology as well as the social sciences. Further progress is hampered by data availability. Issues which need to be addressed include the use of unique patient identifiers (UPIs) to facilitate linkages between separate databases; standardized measurement of the experiences of patients and others; and deepening collaboration between Eurostat, the World Health Organization (WHO), and the Organization for Economic Co-operation and Development (OECD) to facilitate the availability of internationally comparable performance information. Conclusions: This study suggests a number of themes for future research. These include testing and improving: the validity and reliability of performance indicators, especially related to avoidable mortality and other outcome indicators; the effectiveness and efficiency of embedding performance indicators in the various governance, monitoring and management models, and their effect on health systems, services and professionals; and the effectiveness and efficiency of linking performance indicators to other national and international strategies and policies such as accreditation and certification, practice guidelines, audits, quality systems, patient safety strategies, national standards on volume and/or quality, public reporting, pay-for-performance and patient/consumer involvement. The field would benefit from strengthening the clearinghouse function for research findings, training of researchers and appropriate scientific publication media. Results should be systematically shared with policy-makers and managers, and networking stimulated between the growing number of regional and national institutes involved in quality measurement and reporting. </description>
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      <title>Evaluating the effectiveness of an educational and feedback intervention aimed at improving consideration of sex differences in guideline development (Article)</title>
      <link>http://repub.eur.nl/res/pub/28471/</link>
      <pubDate>2010-12-01T00:00:00Z</pubDate>
      <description>Objectives: To investigate the effect of an educational and feedback intervention to enhance consideration of sex differences in clinical guideline development. Design: Preintervention and postintervention questionnaires in intervention and control groups. Content analysis of intervention guidelines and former versions. Setting Guideline consultants, working-group members and guideline documents of two Dutch guidelinedeveloping organisations. Main outcome measures Attitudes of guideline developers concerning the importance of considering sex differences and the number of the sex-specific statements in the contents of guideline documents. Results: The attitude of the intervention group did not change significantly relative to the control group. Consideration of sex-related factors within the guidelines increased relative to available previous versions. Conclusion Education and expert feedback may increase consideration of sex differences in guidelines. Further efforts are needed to implement and test these interventions.</description>
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      <title>Cost-effectiveness of monitoring glaucoma patients in shared care: An economic evaluation alongside a randomized controlled trial (Article)</title>
      <link>http://repub.eur.nl/res/pub/24002/</link>
      <pubDate>2010-11-19T00:00:00Z</pubDate>
      <description>Background. Population aging increases the number of glaucoma patients which leads to higher workloads of glaucoma specialists. If stable glaucoma patients were monitored by optometrists and ophthalmic technicians in a glaucoma follow-up unit (GFU) rather than by glaucoma specialists, the specialists' workload and waiting lists might be reduced. We compared costs and quality of care at the GFU with those of usual care by glaucoma specialists in the Rotterdam Eye Hospital (REH) in a 30-month randomized clinical trial. Because quality of care turned out to be similar, we focus here on the costs. Methods. Stable glaucoma patients were randomized between the GFU and the glaucoma specialist group. Costs per patient year were calculated from four perspectives: those of patients, the Rotterdam Eye Hospital (REH), Dutch healthcare system, and society. The outcome measures were: compliance to the protocol; patient satisfaction; stability according to the practitioner; mean difference in IOP; results of the examinations; and number of treatment changes. Results. Baseline characteristics (such as age, intraocular pressure and target pressure) were comparable between the GFU group (n = 410) and the glaucoma specialist group (n = 405). Despite a higher number of visits per year, mean hospital costs per patient year were lower in the GFU group (€139 vs. €161). Patients' time and travel costs were similar. Healthcare costs were significantly lower for the GFU group (€230 vs. €251), as were societal costs (€310 vs. €339) (p &lt; 0.01). Bootstrap-, sensitivity- and scenario-analyses showed that the costs were robust when varying hospital policy and the duration of visits and tests. Conclusion. We conclude that this GFU is cost-effective and deserves to be considered for implementation in other hospitals. </description>
    </item> <item>
      <title>Diffusing Aviation Innovations in a Hospital in the Netherlands (Article)</title>
      <link>http://repub.eur.nl/res/pub/20106/</link>
      <pubDate>2010-07-19T00:00:00Z</pubDate>
      <description>Background: Many authors have advocated the diffusion of innovations from other high-risk industries into health care to improve safety. The aviation industry is comparable to health care because of its similarities in (a) the use of technology, (b) the requirement of highly specialized professional teams, and (c) the existence of risk and uncertainties. For almost 20 years, The Rotterdam Eye Hospital (Rotterdam, the Netherlands) has been engaged in diffusing several innovations adapted from aviation.

Methods: A case-study methodology was used to assess the application of innovations in the hospital, with a focus on the context and the detailed mechanism for each innovation. Data on hospital performance outcomes were abstracted from the hospital information data management system, quality and safety reports, and the incident reporting system. Information on the innovations was obtained from a document search; observations; and semistructured, face-to-face interviews.

Innovations: Aviation industry-based innovations diffused into patient care processes were as follows: patient planning and booking system, taxi service/valet parking, risk analysis (as applied to wrong-site surgery), time-out procedure (also for wrong-site surgery), Crew Resource Management training, and black box. Observations indicated that the innovations had a positive effect on quality and safety in the hospital: Waiting times were reduced, work processes became more standardized, the number of wrong-site surgeries decreased, and awareness of patient safety was heightened.

Conclusion: A near-20-year experience with aviation-based innovation suggests that hospitals start with relatively simple innovations and use a systematic approach toward the goal of improving safety.</description>
    </item> <item>
      <title>Monitoring of stable glaucoma patients (Research Report)</title>
      <link>http://repub.eur.nl/res/pub/20173/</link>
      <pubDate>2010-07-01T00:00:00Z</pubDate>
      <description></description>
    </item> <item>
      <title>Evaluation of an international benchmarking initiative in nine eye hospitals (Article)</title>
      <link>http://repub.eur.nl/res/pub/17569/</link>
      <pubDate>2010-01-01T00:00:00Z</pubDate>
      <description>Background: Benchmarking has become very popular among managers to improve quality in the private and public sector, but little is known about its applicability in international hospital settings.
Purpose: The purpose of this study was to evaluate the applicability of an international benchmarking initiative in eye hospitals.

Methodology: To assess the applicability, an evaluation frame was constructed on the basis of a systematic literature review. The frame was applied longitudinally to a case study of nine eye hospitals that used a set of performance indicators for benchmarking. Document analysis, nine questionnaires, and 26 semistructured interviews with stakeholders in each hospital were used for qualitative analysis.

Findings: The evaluation frame consisted of four areas with key conditions for benchmarking: purposes of benchmarking, performance indicators, participating organizations, and performance management systems. This study showed that the international benchmarking between eye hospitals scarcely met these conditions. The used indicators were not incorporated in a performance management system in any of the hospitals. Despite the apparent homogeneity of the participants and the absence of competition, differences in ownership, governance structure, reimbursement, and market orientation made comparisons difficult. Benchmarking, however, stimulated learning and exchange of knowledge. It encouraged interaction and thereby learning on the tactical and operational levels, which is also an incentive to attract and motivate staff.

Practice Implications: Although international hospital benchmarking seems to be a rational process of sharing performance data, this case study showed that it is highly dependent on social processes and a learning environment. It can be useful for diagnostics, helping local hospitals to catalyze performance improvements.</description>
    </item> <item>
      <title>Monitoring of stable glaucoma patients (Research Report)</title>
      <link>http://repub.eur.nl/res/pub/39835/</link>
      <pubDate>2010-01-01T00:00:00Z</pubDate>
      <description>A high workload for ophthalmologists and long waiting lists for patients challenge the
organization of ophthalmic care. Tasks that require less specialized skills, like the
monitoring of stable (well controlled) glaucoma patients could be substituted from
ophthalmologists to other professionals (substitution in person). In addition, care
could perhaps be provided in an ambulatory setting (substitution in location of care).
To date, little is known about substituting care in ophthalmology, the organizational
and professional dynamics involved and any consequences for both the quality of
care and cost effectiveness.
Glaucoma is the name given to a group of eye diseases characterized by damage to
the optic nerve yielding gradual, irreversible loss of visual field. Glaucoma is often
related to too high an intraocular pressure (IOP) and is age related. The usual care
for glaucoma patients consists of diagnosis, lifelong monitoring, and treatment and is
provided by ophthalmologists. However, monitoring stable glaucoma patients will
presumably not require the specialist expertise of an ophthalmologist and may be
carried out by less specialized professionals. Therefore, the quality of care given to
stable glaucoma patients was evaluated when provided by ophthalmic technicians or
optometrists based on pre-set protocols and under supervision of ophthalmologists in
a Glaucoma follow-up unit (GFU) within The Rotterdam Eye Hospital (REH).
The objective of this study is to evaluate an organizational intervention, a GFU for
monitoring stable glaucoma patients in a hospital setting, staffed by non-physician
Health Care Professionals instead of ophthalmologists. Furthermore, conditions will
be formulated that need to be fulfilled to successfully substitute the monitoring care
for stable glaucoma patients to a primary care optometrist (substitution in person as
well as in location). The conditions will be based on the experiences with the GFU
(substitution in person only).</description>
    </item> <item>
      <title>Creating patient value in glaucoma care (Article)</title>
      <link>http://repub.eur.nl/res/pub/16555/</link>
      <pubDate>2009-04-01T00:00:00Z</pubDate>
      <description>Purpose: The purpose of this paper is to explore in a specific hospital care process the applicability
in practice of the theories of quality costing and value chains.
Design/methodology/approach: In a retrospective case study an in-depth evaluation of the use of
a quality cost model (QCM) and the applicability of Porter’s care delivery value chain (CDVC) was
performed in a specific care process: glaucoma care over the period 2001 to 2006 in the Rotterdam Eye
Hospital in The Netherlands.
Findings: The case study shows a reduction of costs per product by increasing the number of
outpatient visits and surgery combined with a higher patient satisfaction. Reduction of costs of
non-compliance by using the QCM is small, due to the absence of (external) financial incentives for
both the hospital and individual physicians. For CDVC to be supportive to an integrated quality and
cost management the notion “patient value” needs far more specification as mutually agreed on by the
stakeholders involved and related reimbursement needs to depend on realised outcomes.
Research limitations/implications: The case study just focused on one specific care process in
one hospital. To determine effects in other areas of health care, it is important to study the use andapplicability of the QCM and the CDVC in other care processes and settings.
Originality/value: QCM and a CDVC can be useful tools for hospital management to manage the outcomes on both quality and costs, but impact is dependent on the incentives in the context of the
existing organisational and reimbursement system and asks for an agreed on operationalisation
among the various stakeholders of the notion of patient value.</description>
    </item> <item>
      <title>Flying with doctors: Experiences with the application of 6 techniques from aviation industry in the Rotterdam Eye Hospital (Article)</title>
      <link>http://repub.eur.nl/res/pub/23512/</link>
      <pubDate>2008-10-01T00:00:00Z</pubDate>
      <description>Intoduction. Aviation industry is often put forward as an example in creating safer health care. Comparing aviation and health care, there are similarities in using technology, working with highly specialized professional teams and the need for dealing with risk and uncertainties (Sexton 2000; Powell 2006; Kao &amp; Thomas 2008).
Rhetorical use of the resemblance however, does not directly contribute to the safety of the health care system. To measure the added value of the experiences in aviation for the health care sector, it is preferable to study in detail the use of aviation based principals in daily practice.</description>
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      <title>Long-term outcomes of continuous intrathecal baclofen infusion for treatment of spasticity: A prospective multicenter follow-up study (Article)</title>
      <link>http://repub.eur.nl/res/pub/30193/</link>
      <pubDate>2008-07-01T00:00:00Z</pubDate>
      <description>Long-term outcomes of 115 patients treated with continuous intrathecal baclofen infusion are reported. A prospective follow-up study was conducted in eight centers. Patients were followed up over a 12-month period. The follow-up scores on the three spasticity scales (Ashworth, spasm, and clonus scales) were significantly lower at every follow-up visit in comparison to the intake score, except for the clonus scale scores at 12 months. Improvements in health-related quality of life (EQ-5D) and functionality (SIP-68, functional independence measure) were small and nonsignificant. A significant reduction in severity of self-reported personal problems rating scale was observed. Sixty-six patients had no adverse events. Types of adverse events reported were wound complications (22%), catheter problems (36%), cerebrospinal fluid leakage (25%), and other complications (17%). Intrathecal baclofen reduces spasticity and severity of patient-reported problems but its effect on quality of life and functionality is less apparent. Improvements are desired in selection criteria, design of spinal catheters, and outcome scales. </description>
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      <title>Quality management and patient safety: Survey results from 102 Hungarian hospitals (Article)</title>
      <link>http://repub.eur.nl/res/pub/14372/</link>
      <pubDate>2008-01-01T00:00:00Z</pubDate>
      <description>Objectives: The aim of this study is to describe the development of quality management systems in Hungarian hospitals. It also aims to answer the policy question, whether a separate patient safety policy should be created additional to quality policies, on national as well as hospital level. Method: In 2005, a questionnaire survey was conducted to evaluate the existing quality management systems in all Hungarian hospitals. The relationship between the level of the development of quality management systems, the certification status and the current level of patient safety activities was investigated using linear regression. Quality was measured with the quality management system development score (QMSDS), and patient safety by the number of patient safety activities. Results: 102 of 134 (76%) of the hospitals have returned the questionnaire. The average hospital has 24.5 of 35 core quality activities, and 4 of 11 patient safety activities. There is a statistically significant but weak relationship between the QMSDS and the number of patient safety activities, explaining 12% of the latter's variance. Certification (International Standards Organisation (ISO) and professional standard based) is not significantly related to patient safety. Conclusions: In our study quality by QMSDS is weakly related; however, certification is not significantly related to patient safety. We conclude that separate patient safety policies seem worthwhile to be created for the hospital sector in addition to the ongoing quality improvement efforts in Hungary.</description>
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      <title>Erratum: Comparing health system performance assessment and management approaches in the Netherlands and Ontario, Canada (BMC Health Services Research (2007) 7 (25)) (Article)</title>
      <link>http://repub.eur.nl/res/pub/36917/</link>
      <pubDate>2007-04-11T00:00:00Z</pubDate>
      <description></description>
    </item> <item>
      <title>Comparing health system performance assessment and management approaches in the Netherlands and Ontario, Canada (Article)</title>
      <link>http://repub.eur.nl/res/pub/36927/</link>
      <pubDate>2007-03-12T00:00:00Z</pubDate>
      <description>Background. Given the proliferation and the growing complexity of performance measurement initiatives in many health systems, the Netherlands and Ontario, Canada expressed interests in cross-national comparisons in an effort to promote knowledge transfer and best practise. To support this cross-national learning, a study was undertaken to compare health system performance approaches in The Netherlands with Ontario, Canada. Methods. We explored the performance assessment framework and system of each constituency, the embeddedness of performance data in management and policy processes, and the interrelationships between the frameworks. Methods used included analysing governmental strategic planning and policy documents, literature and internet searches, comparative descriptive tables, and schematics. Data collection and analysis took place in Ontario and The Netherlands. A workshop to validate and discuss the findings was conducted in Toronto, adding important insights to the study. Results. Both Ontario and The Netherlands conceive health system performance within supportive frameworks. However they differ in their assessment approaches. Ontario's Scorecard links performance measurement with strategy, aimed at health system integration. The Dutch Health Care Performance Report (Zorgbalans) does not explicitly link performance with strategy, and focuses on the technical quality of healthcare by measuring dimensions of quality, access, and cost against healthcare needs. A backbone 'five diamond' framework maps both frameworks and articulates the interrelations and overlap between their goals, themes, dimensions and indicators. The workshop yielded more contextual insights and further validated the comparative values of each constituency's performance assessment system. Conclusion. To compare the health system performance approaches between The Netherlands and Ontario, Canada, several important conceptual and contextual issues must be addressed, before even attempting any future content comparisons and benchmarking. Such issues would lend relevant interpretational credibility to international comparative assessments of the two health systems. </description>
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      <title>Quality of stroke prevention in general practice: relationship with practice organization (Article)</title>
      <link>http://repub.eur.nl/res/pub/22478/</link>
      <pubDate>2005-02-01T00:00:00Z</pubDate>
      <description>OBJECTIVE: To investigate the relationship between elements of practice organization related to stroke prevention in general practice, and suboptimal preventive care preceding the occurrence of stroke.

DESIGN: This study was conducted among 69 Dutch general practitioners in the Rotterdam region. Information on the implementation of elements of practice organization related to stroke prevention was collected by postal questionnaire. Data on the process of patient care were collected by means of chart review and interviews with general practitioners. Cases of stroke (n = 186) were retrospectively audited by an expert panel with guideline-based review criteria. Using logistic regression analysis we investigated the relationship between the probability of suboptimal care delivery and the presence of specific elements of practice organization related to stroke prevention (tailored information systems, formal delegation of preventive tasks, standardization of care).

RESULTS: For some elements of practice organization significant relationships with the quality of stroke prevention were found. Suboptimal care was less common among general practitioners with a higher level of noting high risk patients in the patient records (odds ratio 0.30; 95% CI 0.13-0.69, P = 0.01), delegating follow-up visits to support staff (odds ratio 0.42; 95% CI 0.22-0.82, P = 0.01) and compliance with the hypertension guideline (odds ratio 0.57; 95% CI 0.41-0.78, P = &lt;0.001). Except for practice type (general practitioners in health centres less often provided suboptimal care, P = 0.02), no significant relationships with general practitioner and practice characteristics were found.

CONCLUSION: This study shows that general practitioners with a higher level of integrated organizational structures for stroke prevention (record keeping, formal delegation of preventive tasks, guideline compliance) are less likely to deliver suboptimal care.</description>
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      <title>The role of 'confounding by indication' in assessing the effect of quality of care on disease outcomes in general practice: results of a case-control study. (Article)</title>
      <link>http://repub.eur.nl/res/pub/13656/</link>
      <pubDate>2005-01-27T00:00:00Z</pubDate>
      <description>BACKGROUND: In quality of care research, limited information is found on the relationship between quality of care and disease outcomes. This case-control study was conducted with the aim to assess the effect of guideline adherence for stroke prevention on the occurrence of stroke in general practice. We report on the problems related to a variant of confounding by indication, that may be common in quality of care studies. METHODS: Stroke patients (cases) and controls were recruited from the general practitioner's (GP) patient register, and an expert panel assessed the quality of care of cases and controls using guideline-based review criteria. RESULTS: A total of 86 patients was assessed. Compared to patients without shortcomings in preventive care, patients who received sub-optimal care appeared to have a lower risk of experiencing a stroke (OR 0.60; 95% CI 0.24 to 1.53). This result was partly explained by the presence of risk factors (6.1 per cases, 4.4 per control), as reflected by the finding that the OR came much closer to 1.00 after adjustment for the number of risk factors (OR 0.82; 95% CI 0.29 to 2.30). Patients with more risk factors for stroke had a lower risk of sub-optimal care (OR for the number of risk factors present 0.76; 95% CI 0.61 to 0.94). This finding represents a variant of 'confounding by indication', which could not be fully adjusted for due to incomplete information on risk factors for stroke. CONCLUSIONS: At present, inaccurate recording of patient and risk factor information by GPs seriously limits the potential use of a case-control method to assess the effect of guideline adherence on disease outcome in general practice. We conclude that studies on the effect of quality of care on disease outcomes, like other observational studies of intended treatment effect, should be designed and performed such that confounding by indication is minimized.</description>
    </item> <item>
      <title>How safe is the safety paradigm? (Article)</title>
      <link>http://repub.eur.nl/res/pub/13413/</link>
      <pubDate>2004-01-01T00:00:00Z</pubDate>
      <description>This paper reviews safety initiatives in the health systems of the UK,
      Canada, Australia, and the US. Initiatives to tackle safety shortcomings
      involve public-private collaborations. Patient safety agencies (to
      institute learning, action and safety culture), adverse event reporting
      and, to a lesser extent, safety related performance indicators are
      currently used to design safer health systems. Their benefits are mixed,
      but there is little debate as to their possible side effects. Foreseeable
      adverse effects of multiple safety organisations stem from them being too
      many, too vague, too narrowly focused, threatened by the medical practice
      environment, and too optimistic. Safety related performance indicators are
      most developed in the US but suffer from inadequacies of administrative
      data, underreporting, variable indicator definitions, "extended" use, and
      low sensitivity of the diagnosis coding system, and arguable
      preventability of the prescribed conditions. A critical appraisal of the
      implications of these deficiencies is important to assure the safety of
      current health system safety initiatives and to establish evidence based
      safety. It is necessary to embed health system safety (as well as patient
      safety) in the societal culture, structures, and policies which promote
      effective, user centred, high performance care while allowing for healthy
      innovation.</description>
    </item> <item>
      <title>Deprivation and systematic stroke prevention in general practice: an audit among general practitioners in the Rotterdam region, The Netherlands (Article)</title>
      <link>http://repub.eur.nl/res/pub/22491/</link>
      <pubDate>2003-12-01T00:00:00Z</pubDate>
      <description>BACKGROUND: To investigate differences in quality of preventive care provided by general practitioners (GPs) to patients at risk of stroke living in deprived and non-deprived neighbourhoods in the Rotterdam region.

METHODS: A 'deprivation score' was used to categorize neighbourhoods according to their deprivation status. Data on the process of patient care were collected by means of chart review and interviews with GPs. Cases of stroke (n=188) were retrospectively audited by an expert panel with guideline-based review criteria. To measure differences in quality of patient care between neighbourhoods, deprivation scores were related to scores for sub-optimal care.

RESULTS: After adjustment for socio-demographic characteristics, patients in deprived neighbourhoods had an increased risk (OR 1.95 (95% CI: 0.98-3.90)) of having received sub-optimal preventive care if compared with patients in non-deprived neighbourhoods. This excess risk was limited to women (OR 3.57 (95% CI: 1.39-9.16) vs OR 1.01 (95% CI: 0.41-2.48) in men). Adjustment for socio-demographic characteristics and risk factor distribution did not change the OR for women to receive sub-optimal care significantly (OR 3.21 (95% CI: 1.24-8.31)). Sub-optimal care originated mainly from deficiencies in follow-up of treated hypertensive and diabetes patients and evaluation of patients' cardiovascular risk profile. Among treated hypertensive women in deprived neighbourhoods who received sub-optimal care, the mean number of deficiencies related to follow-up was almost double that of the corresponding group in non-deprived neighbourhoods.

CONCLUSION: Quality of care to prevent stroke in general practice differs considerably between deprived and non-deprived neighbourhoods. Patients in deprived neighbourhoods, and women in particular, have almost twice the risk of receiving sub-optimal preventive care.</description>
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      <title>Quality management of medical specialist care in the Netherlands : an explorative study of its nature and development (Doctoral Thesis)</title>
      <link>http://repub.eur.nl/res/pub/22684/</link>
      <pubDate>1996-11-06T00:00:00Z</pubDate>
      <description>In January 1985, the author of this study was employed as a scientific staff member
at CBO, the Dutch National Organisation for Quality Assurance in Hospitals. His
main job was to support peer review committees of medical specialists in hospitals.
The task proved to be challenging and was broadened to an active involvement in
the consensus development programme run by CBO'S scientific council. Both peer
review and guideline development through consensus conferences turned out to be far
more complex activities than might be expected at first sight. Hence over the years the
ambition emerged to study these phenomena more thoroughly. From the beginning it
was clear that peer review and guideline development are only two of the various
systematic activities the medical profession has developed to manage the quality of
specialist care. This study is rooted in the curiosity to understand these activities and
in its essence the study tries to provide an answer to two questions:
• What is quality management of medical specialist care?
• How does it develop?</description>
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