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motif interaction fxxlf receptor binding ar fxxlf motif androgen ar lbd lxxll peptide coactivator protein sequence residue • ar recognition fragment activity expression androgen receptor fxxlf motif groove novel androgen-speci fic experiment +4·6 yeast lncap element lxxll motifs endocrinology response position domain f 23l wild-type journal structure variant hep 3b cells model speci substitution recognition candidate ␣ lbd acid residues endocrinol presence positions ϩ1 ar lbd interaction - galactosidase activity f residues assay luciferase tif 2 boxes are-sarg dubbink candidate ares lncap cells androgen-speci fusion hormone others · sarg enhancer factor prostate k 720 promoter study mutation transcriptional november downloaded september chain analysis coactivator lxxll motifs ar coactivator groove e 897 tif 2 motifs luciferase activity
2 Most Recent Publications
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A bioinformatics-based functional analysis shows that the specifically androgen-regulated gene SARG contains an active direct repeat androgen response element in the first intron.
(Article)
Steketee, K. Ziel-van der Made, C.J. Korput, H.A.G.M. van der Houtsmuller, A.B. Trapman, J. |
2004-10-01
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Distinct recognition modes of FXXLF and LXXLL motifs by the androgen receptor.
(Article)
Dubbink, H.J. Hersmus, R. Verma, C.S. Korput, H.A.G.M. van der Berrevoets, C.A. Tol, J. van Ziel-van der Made, C.J. Brinkmann, A.O. Pike, A.C. Trapman, J. |
2004-09-01
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