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receptor androgen activity phosphorylation mutation interaction binding domain assay activation protein androgen receptor expression isoform sequence usf 1 presence fraction sample wild-type virus peptide fication promoter residue study region ligand n /c interaction wild-type ar result q 902k mutation transcriptional diarrhea identi f 826l patient analysis ar f 826l transcription hepg 2 cells cho cells /well transactivation tif 2 ar q 902k endocrinol astroviru r 1881 picobirnaviruse picobirnaviru e-box brinkmann hormone concentration increase function transcriptional activity usf 2 ser -650 factor nc-tdi diarrhea samples phosphorylated transfected amount ampli substitution 110 kda isoform sequence-independent ampli fication trapman renilla luc activity hl gene vector disease tif 2 co-activation phosphosite 112 kda isoform pusf 1 hepatic
7 Most Recent Publications
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Human astrovirus infection in a patient with new-onset celiac disease
(Article)
Smits, S.L. Leeuwen, M. van Eijck, A.A. van der Fraaij, P.L.A. Escher, J.C. Simon, J.H. Osterhaus, A.D.M.E. |
2010-09-01
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Human picobirnaviruses identified by molecular screening of diarrhea samples
(Article)
Leeuwen, M. van Williams, M.M. Koraka, P. Simon, J.H. Smits, S.L. Osterhaus, A.D.M.E. |
2010-05-01
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Attention Problems, Inhibitory Control, and Intelligence Index Overlapping Genetic Factors: A Study in 9-, 12-, and 18-Year-Old Twins
(Article)
Polderman, T.J.C. Geus, E.J.C. de Hoekstra, R. Bartels, M.C. Leeuwen, M. van Verhulst, F.C. Posthuma, D. Boomsma, D.I. |
2009-05-01
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Upstream Stimulatory Factors 1 and 2 activate the human hepatic lipase promoter via E-box dependent and independent mechanisms
(Article)
Deursen, D. van Leeuwen, M. van Vaulont, S. Jansen, H. Verhoeven, A.J.M. |
2009-04-01
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A novel mutation F826L in the human androgen receptor in partial androgen insensitivity syndrome; increased NH2-/COOH-terminal domain interaction and TIF2 co-activation
(Article)
Wong, H.Y. Hoogerbrugge, J.W. Wolffenbuttel, K.P. Trapman, J. Kleijer, W.J. Drop, S.L.S. Grootegoed, J.A. Brinkmann, A.O. Pang, K.L. Leeuwen, M. van Royen, M.E. van Molier, M. Berrevoets, C.A. Dooijes, D. Dubbink, H.J. Wijngaart, D.J. van de |
2008-09-24
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Functional analysis of a novel androgen receptor mutation, Q902K, in an individual with partial androgen insensitivity.
(Article)
Umar, A. Berrevoets, C.A. Van, N.M. Leeuwen, M. van Verbiest, M. Kleijer, W.J. Dooijes, D. Grootegoed, J.A. Drop, S.L.S. Brinkmann, A.O. |
2005-01-01
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Phosphorylation of androgen receptor isoforms
(Article)
Wong, H.Y. Burghoorn, J.A. Brinkmann, A.O. Trapman, J. Leeuwen, M. van Ruiter, P.E. de Schippers, E. Blok, L.J. Li, K.W. Dekker, H.L. Jong, L. de Grootegoed, J.A. |
2004-10-15
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